Results 91 to 100 of about 1,230,040 (315)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

DEFB4A/hBD2, a non-invasive serum biomarker for detection of ulcerative colitis

open access: yesScientific Reports
The ulcerative colitis (UC) is a chronic episodic relapsing, and remitting inflammatory bowel disease with increasing frequency worldwide. Along with colonoscopy, faecal calprotectin (FCP) > 150 µg/g, elevated faecal Lactoferrin or elevated CRP are now ...
Soumyabrata Chatterjee   +8 more
doaj   +1 more source

Analysis of IL2/IL21 Gene Variants in Cholestatic Liver Diseases Reveals an Association with Primary Sclerosing Cholangitis [PDF]

open access: yes, 2011
Background/Aims: The chromosome 4q27 region harboring IL2 and IL21 is an established risk locus for ulcerative colitis (UC) and various other autoimmune diseases.
Denk, Gerald Ulrich   +15 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Impact of body mass index on the outcomes of endoscopic retrograde cholangiopancreatography: a systematic review and network meta-analysis [PDF]

open access: yesClinical Endoscopy
Background/Aims: Obesity is an increasing health concern worldwide, and an elevated body mass index (BMI) may influence the outcomes of endoscopic retrograde cholangiopancreatography (ERCP).
Erfan Arabpour   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Fatty liver syndrome in captive bustards: Clinical, pathological and epidemiological findings

open access: yes, 1997
Clinical, pathological, and epidemiological findings are presented on fatty liver syndrome mainly in houbara bustards (Chlamydotis undulata macqueenii), but also in some other bustard species.
Nicholls, P.K.   +2 more
core  

Neurodevelopmental Outcomes in Children With Liver Diseases:A Systematic Review [PDF]

open access: yes, 2018
Objective: The aim of the study was to determine the neurodevelopmental outcomes of children with liver diseases based on a systematical review of the literature.
Janneke L.M. Bruggink   +13 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

STUDIES ON THE ELECTROCARDIOGRAM IN LIVER DISEASE VECTORCARDIOGRAM IN LIVER DISEASE

open access: yesNihon Naika Gakkai Zasshi, 1964
肝疾患と心臓との関係を究明するため,肝疾患患者のベクトル心電図を木村法(148例), Frank法(22例)により撮影し,これらと肝機能,血清蛋白,血清電解質および心電図を比較検討した. QRS, T環最大ベクトルの大きさは急性肝炎,慢性肝炎,肝硬変症の順に小となり, QRS-T夾角は逆の順に大となる.また, QRS, T環最大ベクトルの大きさは,肝機能障害の強くなるにつれ,また血清蛋白のうちγ-globulinの増加群で小となる.この関係はとくにT環で著しい.
openaire   +3 more sources

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