Results 101 to 110 of about 1,230,040 (315)

Liver Development, Regeneration, and Carcinogenesis [PDF]

, 2010
The identification of putative liver stem cells has brought closer the previously separate fields of liver development, regeneration, and carcinogenesis. Significant overlaps in the regulation of these processes are now being described.
Ross, James A, Kung, Janet W C, Currie, Ian S, Stuart J. Forbes, Forbes, Stuart J, Janet W. C. Kung, Ian S. Currie, James A. Ross   +7 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Prophylactic Biliary Stenting After Stone Clearance Improves the Safety of Needle‐Knife Fistulotomy: A Propensity Score‐Matched Analysis

JGH Open
Objectives Needle‐knife fistulotomy is an advanced technique for gaining biliary access in endoscopic retrograde cholangiopancreatography (ERCP). This study assesses the hypothesis of whether biliary stenting after needle‐knife fistulotomy could improve ...
Amir Sadeghi, Erfan Arabpour, Mohammad Abdehagh, Mohammad Reza Zali   +3 more
doaj   +1 more source

A consortium of Hordeum vulgare and gut microbiota against non-alcoholic fatty liver disease via data-driven analysis

Artificial Cells, Nanomedicine, and Biotechnology
Despite many recent studies on non-alcoholic fatty liver disease (NAFLD) therapeutics, the optimal treatment has yet to be determined. In this unfinished project, we combined secondary metabolites (SMs) from the gut microbiota (GM) and Hordeum vulgare ...
Su-Been Lee, Haripriya Gupta, Byeong-Hyun Min, Raja Ganesan, Satya Priya Sharma, Sung-Min Won, Jin-Ju Jeong, Min-Gi Cha, Goo-Hyun Kwon, Min-Kyo Jeong, Ji-Ye Hyun, Jung-A Eom, Hee-Jin Park, Sang-Jun Yoon, Sang Youn Lee, Mi-Ran Choi, Dong Joon Kim, Ki-Kwang Oh, Ki-Tae Suk   +18 more
doaj   +1 more source

Factors in perioperative care that determine blood loss in liver surgery [PDF]

, 2012
Excessive blood loss during liver surgery contributes to postoperative morbidity and mortality and the minimizing of blood loss improves outcomes. This study examines pre- and intraoperative factors contributing to blood loss and identifies areas for ...
McNally, Stephen J, McKeown, Dermot W, Parks, Rowan W; id_orcid, Garden, O. James, Parks, Rowan W., Revie, Erica J, Revie, Erica J., Garden, O James, McKeown, Dermot W., Massie, Lisa J, McNally, Stephen J., Wigmore, Stephen J, Wigmore, Stephen J., Massie, Lisa J.   +13 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

A network meta-analysis of optimal strategies for preventing post-endoscopic retrograde cholangiopancreatography pancreatitis

Scientific Reports
Numerous interventions have been proposed to reduce the risk of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP), but it remains uncertain which approach is the most effective.
Erfan Arabpour, Alireza Azarboo, Amirreza Pouladi, Parya Mozafari Komesh-Tape, Fatemeh Mousavi Eshlaghi, Hadi Golmoradi, Amirhossein Ghaseminejad-Raeini, Amir Sadeghi, Mohammad Reza Zali   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Gastrointestinal bleeding risk in cirrhotic portal vein thrombosis: focus on thrombus extension to superior mesenteric vein

BMC Gastroenterology
Background & aims Portal vein thrombosis (PVT) is a prevalent cirrhosis complication linked to gastrointestinal bleeding. This study aims to assess correlations between PVT classification and the risk of bleeding in patients with cirrhotic PVT.
Sa Lv, Hui Feng, Tianjiao Xu, Hua Tian, Haibo Wang, Dongze Li, Shaoli You, Bing Zhu   +7 more
doaj   +1 more source