Results 51 to 60 of about 1,831,704 (212)

Melatonin inhibits bile acids-initiated Cxcl2 expression through JNK/c-Jun signalling pathway

open access: yesDi-san junyi daxue xuebao, 2022
Objective To investigate the underlying molecular mechanism by which melatonin suppresses bile acids (BAs)-initiated expression of chemokine C-X-C motif chemokine ligand 2 (Cxcl2). Methods Mice were fed a 1% cholic acid (CA)-supplemented diet for 2 weeks
TAN Ya   +5 more
doaj   +1 more source

SerpinB3 promotes pro-fibrogenic responses in activated hepatic stellate cells [PDF]

open access: yes, 2017
SerpinB3 is a hypoxia- and hypoxia-inducible factor-2\u3b1-dependent cystein protease inhibitor that is up-regulated in hepatocellular carcinoma and in parenchymal cells during chronic liver diseases (CLD). SerpinB3 up-regulation in CLD patients has been
Albano, Emanuele   +16 more
core   +3 more sources

Combination of TACE and Sorafenib Improves Outcomes in BCLC Stages B/C of Hepatocellular Carcinoma: A Single Centre Experience

open access: yesAnnals of Hepatology, 2017
Background & Aim. Transarterial chemoembolization (TACE) or sorafenib is recommended for hepatocellular carcinoma BCLC stages B and C respectively. We studied the role of combination of TACE and sorafenib in BCLC stages B/C.Material and methods.
Joy Varghese   +9 more
doaj   +1 more source

The prevalence of the elevation serum alanine amino transaminase at gorgan in Northern Iran [PDF]

open access: yes, 2011
The elevation of serum alanine aminotranferase levels is associated most commonly with some forms of liver diseases. The aim of this study was to determine the prevalence of elevated serum alanine aminotransferase levels and the possible liver damages in
Mansourian, A.R.   +2 more
core  

Transplantation in children [PDF]

open access: yes, 1976
Kidney transplantation in very young children, less than 2 years of age, has usually failed, mainly because of difficulties maintaining these patients on hemodialysis long enough to permit retransplantation after loss of the original graft.
Charles W. Putnam   +15 more
core   +1 more source

Severe combined immunodeficiency: improved survival leading to detection of underlying liver disease

open access: yesBMC Gastroenterology, 2023
Background Adenosine deaminase deficiency (ADA) is an autosomal recessive disorder leading to severe combined immunodeficiency (SCID). It is characterized patho-physiologically by intracellular accumulation of toxic products affecting lymphocytes.
Anusha Vittal   +9 more
doaj   +1 more source

Orthotopic liver transplantation for fulminant and subacute hepatic failure [PDF]

open access: yes, 1988
Fulminant and subacute hepatitis are conditions characterized by rapid liver failure, which can lead to death in 80 to more than 95% of the cases with medical supportive care only.
Iwatsuki, S, Starzl, TE, Stieber, AC
core  

Perinatal Gene Transfer to the Liver [PDF]

open access: yes, 2011
The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM   +6 more
core   +1 more source

Analysis of Association between IL-17 gene rs2275913 Single Nucleotide Polymorphism and Chronic Hepatitis B Infection

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2018
BACKGROUND AND OBJECTIVE: Hepatitis B disease is one of the main causes of inflammation and liver damage that can lead to chronic hepatitis B virus infection.
H Tayefinasrabadi   +7 more
doaj  

Global prevalence, incidence, and outcomes of alcohol related liver diseases: a systematic review and meta-analysis

open access: yesBMC Public Health, 2023
Background Alcohol related liver disease (ARLD) is one of the major chronic liver diseases worldwide. This review aimed to describe the global prevalence, incidence, and outcomes of ARLD.
Xuanxuan Niu   +7 more
doaj   +1 more source

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