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Approach to Elevated Liver Enzymes

Primary Care: Clinics in Office Practice, 2023
Abnormal liver tests are one of the most common challenges in the primary care setting. Primary care practitioners order these tests for numerous reasons, including investigating abdominal signs and symptoms or suspected alcohol-use disorder, or to determine medication adverse effects.
Jessica, Rosenberg   +2 more
openaire   +2 more sources

Implication of normal liver enzymes in liver disease

Journal of Viral Hepatitis, 2009
Summary.  Chronic liver disease is usually asymptomatic until its late stages and also significant hepatic necroinflammation and fibrosis may be present in persistently normal ALT levels HBV, HCV carriers or similarly, in patients with nonalcoholic fatty liver disease.
CALVARUSO, Vincenza, CRAXI, Antonio
openaire   +3 more sources

Liver Enzyme Ratios in Neonatal Liver Disease

European Journal of Pediatric Surgery, 1984
The gamma-GT/ASAT (aspartate aminotransferase) and gamma-GT/ALAT (alanine aminotransferase) ratios were examined in 6 children with neonatal hepatitis (NH), 14 children with extrahepatic biliary atresia (EHBA), and 8 children with intrahepatic cholestasis (IHC) (of which 3 with the Aagenaes syndrome). A ratio above 1 is suggestive of EHBA.
T W, Hansen, E, Monn
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Enzyme Activities in Human Liver

Enzymologia biologica et clinica, 1970
SummaryBiologic, technical, and methodic problems in the determination of enzyme activities in human hepatic tissue are evaluated critically and enzyme activities of normal liver, as well as their ...
E, Schmidt, F W, Schmidt
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Interpretation of Liver Enzymes

Veterinary Clinics of North America: Small Animal Practice, 2007
Abnormalities in liver enzymes are commonly encountered in clinical practice. Knowledgeable assessment requires a full understanding of their pathophysiology and provides an important means of detecting the earliest stage of many serious hepatobiliary disorders.
openaire   +2 more sources

Release of Enzymes from the Liver

Nature, 1967
DIFFERENT lesions of an organ lead to distinct enzyme patterns in the serum. Our knowledge about the mechanisms affecting the release of cellular enzymes from damaged tissues, however, is poor.
E, Schmidt, F W, Schmidt
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Furosemide and Increases in Liver Enzymes

Annals of Internal Medicine, 1988
Excerpt To the Editor:Acute increases (hepatitis-like) in liver enzymes, without clinical evidence of viral hepatitis, have been reported only occasionally and have been termed ischmic hepatitis (1...
I, Lang   +5 more
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Liver Enzymes and Liver Biopsy

Annals of Internal Medicine, 1990
Excerpt To the Editor:As an office-based community internist, I believe that the conclusion in the article by Van Ness and Diehl (1) that liver biopsies are helpful in evaluating liver enzyme abnor...
openaire   +1 more source

Liver Enzymes in Biliary Retention

Nature, 1962
THE toxicity of bilirubin has been demonstrated in animals. It is known to inhibit brain respiration in vitro1, and to uncouple oxidative phosphorylation in isolated mitochondrias2. Its cytotoxic action on almost every cell in the animal has been recently emphasized by Rozdilsky3.
V, SCHWARZMANN, C, COUINAUD, N, BERTHAUX
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Pigeon liver malic enzyme

Molecular and Cellular Biochemistry, 1982
Malic enzyme of pigeon liver is a tetrameric molecule with identical, or nearly-identical subunits. It catalyzes, in addition to oxidative decarboxylation of L-malate, the following metal activated component reactions: Oxalacetate decarboxylase; reductase with broad specificity on α-ketocarboxylic acids; a NADP+-dependent dismutation of L-malate to L ...
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