Results 241 to 250 of about 865,411 (286)
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New England Journal of Medicine, 2013
Untreated acute liver failure (ALF) has a poor outcome and so rapid diagnosis and management is vital if the patient is to survive. ALF has such profound and widespread physiological consequences that whenever possible, patients with ALF should be managed in an intensive care unit. Management is to support the physiology and treat the underlying cause.
William Bernal +2 more
exaly +3 more sources
Untreated acute liver failure (ALF) has a poor outcome and so rapid diagnosis and management is vital if the patient is to survive. ALF has such profound and widespread physiological consequences that whenever possible, patients with ALF should be managed in an intensive care unit. Management is to support the physiology and treat the underlying cause.
William Bernal +2 more
exaly +3 more sources
Critical Care Nursing Quarterly, 2022
Acute liver failure (ALF) is a rare but life-threatening disease process that can result in rapidly progressive encephalopathy, elevated intracranial pressure, and multiorgan failure. In the United States, the 2 most common causes of ALF in the intensive care unit (ICU) are acetaminophen overdose and hypoxic-ischemic hepatopathy.
Chelsea, Ledgerwood +4 more
openaire +4 more sources
Acute liver failure (ALF) is a rare but life-threatening disease process that can result in rapidly progressive encephalopathy, elevated intracranial pressure, and multiorgan failure. In the United States, the 2 most common causes of ALF in the intensive care unit (ICU) are acetaminophen overdose and hypoxic-ischemic hepatopathy.
Chelsea, Ledgerwood +4 more
openaire +4 more sources
Liver Failure, Acute-on-Chronic
Encyclopedia of Gastroenterology, 2020Acute-on-Chronic Liver Failure Acute decompensation in patients with chronic liver disease is called acute-on-chronic liver failure.
V. Arroyo, J. Clària, J. Trebicka
semanticscholar +2 more sources
Pediatric Annals, 2016
Pediatric acute liver failure (ALF) is a complex and rapidly progressive syndrome that results from a variety of age-dependent etiologies. It is defined by the acute onset of liver disease with no evidence of chronic liver disease. There must be biochemical or clinical evidence of severe liver dysfunction as defined by an international ...
Ami, Grek, Lisa, Arasi
openaire +4 more sources
Pediatric acute liver failure (ALF) is a complex and rapidly progressive syndrome that results from a variety of age-dependent etiologies. It is defined by the acute onset of liver disease with no evidence of chronic liver disease. There must be biochemical or clinical evidence of severe liver dysfunction as defined by an international ...
Ami, Grek, Lisa, Arasi
openaire +4 more sources
Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis
Gut, 2021Background and aims Acute-on-chronic liver failure (ACLF) is characterised by acute decompensation of cirrhosis associated with organ failures. We systematically evaluated the geographical variations of ACLF across the world in terms of prevalence ...
G. Mezzano +9 more
semanticscholar +1 more source
Acute-on-chronic liver failure: A distinct clinical syndrome.
Journal of Hepatology, 2021There are different operating definitions for acute-on-chronic liver failure (ACLF) in different geographic regions. Consortia in Western countries have developed definitions that apply to patients with cirrhosis, while consortia in Asia have developed ...
R. Moreau +4 more
semanticscholar +1 more source
Current Opinion in Gastroenterology, 2001
Worldwide, viral hepatitis is the leading cause of acute liver failure, whereas acetaminophen hepatotoxicity is the most commonly identified cause in Western countries. Restricting the quantity of acetaminophen tablets dispensed has been shown to reduce morbidity and mortality in countries with a high incidence of acetaminophen overdose.
R J, Fontana, L G, Quallich
openaire +4 more sources
Worldwide, viral hepatitis is the leading cause of acute liver failure, whereas acetaminophen hepatotoxicity is the most commonly identified cause in Western countries. Restricting the quantity of acetaminophen tablets dispensed has been shown to reduce morbidity and mortality in countries with a high incidence of acetaminophen overdose.
R J, Fontana, L G, Quallich
openaire +4 more sources
New England Journal of Medicine, 2000
Worldwide, viral infection is responsible for the majority of cases of acute liver failure, and the presence of co-existing chronic viral hepatitis may increase its severity. The newly described hepatotrophic viruses, hepatitis G virus and transfusion-transmitted virus, are unlikely to be major aetiological agents.
Bernal, W, Wendon, J
openaire +7 more sources
Worldwide, viral infection is responsible for the majority of cases of acute liver failure, and the presence of co-existing chronic viral hepatitis may increase its severity. The newly described hepatotrophic viruses, hepatitis G virus and transfusion-transmitted virus, are unlikely to be major aetiological agents.
Bernal, W, Wendon, J
openaire +7 more sources