Results 11 to 20 of about 568,379 (312)

Psoas Muscle Index Can Be Used to Predict Long-Term Mortality in Young Male Patients With Acute-on-Chronic Liver Failure

Frontiers in Nutrition, 2022
ObjectiveThe use of psoas muscle index (PMI) in acute-on-chronic liver failure (ACLF) has not been reported, and the aim of this study was to evaluate the predictive value of PMI for the prognosis of patients with ACLF.MethodsIn this study, male ACLF ...
Manman Xu, Manman Xu, Tongzeng Li, Ming Kong, Ming Kong, Nan Geng, Nan Geng, Wenyan Song, Guanya Guo, Zhongping Duan, Zhongping Duan, Ying Han, Yu Chen, Yu Chen   +13 more
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Kuhuang injection exerts a protective effect by activating PPAR-γ in an in vitro model of chlorpromazine-induced cholestatic liver injury constructed by tissue engineering

Pharmaceutical Biology, 2022
Context Kuhuang (KH) injection is a widely used anticholestatic drug in the clinic and the mechanisms are still unclear.Objective This study uses a new 3D tissue-engineered (TE) liver platform to study the ability of kuhuang to ameliorate liver injury ...
Qiao Wu, Zhongping Duan, Long Huang, Zhijie Li   +3 more
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Acute Liver Failure [PDF]

Seminars in Respiratory and Critical Care Medicine, 1993
Acute liver failure (ALF) (sometimes referred to as fulminant hepatic failure) is a clinical syndrome from a variety of causes resulting from rapid loss in hepatocyte function, typically associated with coagulopathy and encephalopathy in a patient without preexisting liver disease or cirrhosis. Cerebral edema is a cardinal feature and may produce uncal
openaire   +4 more sources

High-dependency units play a key role in the treatment of a Chinese military patient who developed liver failure while abroad

Military Medical Research, 2019
High-dependency units (HDUs) provide high-level care to patients who suffer from single organ failure, with the exception of respiratory failure requiring mechanical ventilation; HDUs serve as an intermediary between general wards and Intensive Care ...
Chen Li, Hai-Bin Su, Xiao-Yan Liu, Li-Na Zhang, Jin-Hua Hu   +4 more
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Combined Effects of UGT1A1 and SLCO1B1 Variants on Chinese Adult Mild Unconjugated Hyperbilirubinemia

Frontiers in Genetics, 2019
The potential for genetic variation to cause adult unconjugated hyperbilirubinemia is increasingly being recognized. However, the cumulative effects of genetic variants have not been fully illuminated.
Jie Bai, Jie Bai, Lei Luo, Shuang Liu, Chen Liang, Chen Liang, Li Bai, Yu Chen, Yu Chen, Sujun Zheng, Sujun Zheng, Zhongping Duan, Zhongping Duan   +12 more
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Negative impact of the pandemic on hospital admissions, morbidity and early mortality for acute cirrhosis decompensation

BMJ Open Gastroenterology, 2023
Introduction The global pandemic has diverted resources away from management of chronic diseases, including cirrhosis. While there is increasing knowledge on COVID-19 infection in liver cirrhosis, little is described on the impact of the pandemic on ...
Rajeshwar P Mookerjee, Kohilan Gananandan, Konstantin Kazankov, Alexandra Phillips, Hannah Old, Anmol Chikhlia, Ishrat Hussain, Sharmaine Jia Ying Sim, Niharika Thakur   +8 more
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Post-Transcriptional Regulation of Hepatic DDAH1 with TNF Blockade Leads to Improved eNOS Function and Reduced Portal Pressure In Cirrhotic Rats

Scientific Reports, 2017
Portal hypertension (PH) is a major cause of morbidity and mortality in chronic liver disease. Infection and inflammation play a role in potentiating PH and pro-inflammatory cytokines, including TNF, are associated with severity of PH.
V. Balasubramanian, G. Mehta, H. Jones, V. Sharma, N. A. Davies, R. Jalan, R. P. Mookerjee   +6 more
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Upregulation of Serum Sphingosine (d18:1)-1-P Potentially Contributes to Distinguish HCC Including AFP-Negative HCC From Cirrhosis

Frontiers in Oncology, 2020
BackgroundSerum sphingolipids are widely involved in the development of hepatocellular carcinoma (HCC). We investigated the serum sphingolipid profile in patients with HCC or cirrhosis and explored the potential diagnostic efficiency of serum ...
Yingying Jiang, Yingying Jiang, Cai Tie, Yang Wang, Yang Wang, Dandan Bian, Dandan Bian, Mei Liu, Mei Liu, Ting Wang, Ting Wang, Yan Ren, Yan Ren, Shuang Liu, Shuang Liu, Li Bai, Li Bai, Yu Chen, Yu Chen, Zhongping Duan, Zhongping Duan, Sujun Zheng, Sujun Zheng, Jinlan Zhang   +23 more
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Mitochondrial Dysfunction in Advanced Liver Disease: Emerging Concepts

Frontiers in Molecular Biosciences, 2021
Mitochondria are entrusted with the challenging task of providing energy through the generation of ATP, the universal cellular currency, thereby being highly flexible to different acute and chronic nutrient demands of the cell.
Ingrid W. Zhang, Ingrid W. Zhang, Cristina López-Vicario, Cristina López-Vicario, Cristina López-Vicario, Marta Duran-Güell, Marta Duran-Güell, Joan Clària, Joan Clària, Joan Clària, Joan Clària   +10 more
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Association of Serum Bilirubin With Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis

Frontiers in Endocrinology, 2022
ObjectiveMetabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD) are the leading chronic diseases worldwide. There are still many controversies about the association between serum bilirubin and MetS or NAFLD.
Chen Liang, Chen Liang, Zhiyuan Yu, Zhiyuan Yu, Li Bai, Li Bai, Wei Hou, Shan Tang, Shan Tang, Wei Zhang, Xinyue Chen, Zhongjie Hu, Zhongping Duan, Zhongping Duan, Sujun Zheng   +14 more
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