Results 21 to 30 of about 1,117,240 (298)

Combined Effects of UGT1A1 and SLCO1B1 Variants on Chinese Adult Mild Unconjugated Hyperbilirubinemia

Frontiers in Genetics, 2019
The potential for genetic variation to cause adult unconjugated hyperbilirubinemia is increasingly being recognized. However, the cumulative effects of genetic variants have not been fully illuminated.
Jie Bai, Jie Bai, Lei Luo, Shuang Liu, Chen Liang, Chen Liang, Li Bai, Yu Chen, Yu Chen, Sujun Zheng, Sujun Zheng, Zhongping Duan, Zhongping Duan   +12 more
doaj   +1 more source

Severe drug-induced liver injury associated with prolonged use of Linezolid [PDF]

, 2010
This study aims to describe a patient developing concomitant severe liver failure and lactic acidosis after long-term treatment with linezolid. A 55-year-old Caucasian woman developed concomitant severe liver failure and lactic acidosis after a treatment
Benoit, Dominique, De Bus, Liesbet, Depuydt, Pieter, Libbrecht, Louis, NOLLET, JOKE, Van Vlierberghe, Hans, Vandekerckhove, Linos, Vogelaers, Dirk   +7 more
core   +1 more source

Post-Transcriptional Regulation of Hepatic DDAH1 with TNF Blockade Leads to Improved eNOS Function and Reduced Portal Pressure In Cirrhotic Rats

Scientific Reports, 2017
Portal hypertension (PH) is a major cause of morbidity and mortality in chronic liver disease. Infection and inflammation play a role in potentiating PH and pro-inflammatory cytokines, including TNF, are associated with severity of PH.
V. Balasubramanian, G. Mehta, H. Jones, V. Sharma, N. A. Davies, R. Jalan, R. P. Mookerjee   +6 more
doaj   +1 more source

Donor gender does not affect liver transplantation outcome in children [PDF]

, 1990
The liver is recognized as a sex hormone-responsive organ. Gender-specific differences in liver function are known to exist. Recently, a higher failure rate for organs transplanted in adults from female donors to male recipients has been reported.
Gavaler, JS, Pillay, P, Starzl, TE, Van Thiel, DH   +3 more
core   +1 more source

Orthotopic liver transplantation in human-immunodeficiency-virus-positive patients in Germany [PDF]

, 2012
Objectives: This summary evaluates the outcomes of orthotopic liver transplantation (OLT) of HIV-positive patients in Germany. Methods: Retrospective chart analysis of HIV-positive patients, who had been liver-transplanted in Germany between July ...
Anadol, Evrim, Beckebaum, Susanne, Berg, C., Bickel, Markus, Ganten, Tom M., Hitzenbichler, Florian, Kalff, Jörg C., Kittner, Jens Martin, Manekeller, Steffen, Paul, Andreas, Radecke, Klaus, Rockstroh, Jürgen, Sauerbruch, Tilman, Spengler, Ulrich, Stoll, Matthias, Zoufaly, Alexander   +15 more
core   +2 more sources

Upregulation of Serum Sphingosine (d18:1)-1-P Potentially Contributes to Distinguish HCC Including AFP-Negative HCC From Cirrhosis

Frontiers in Oncology, 2020
BackgroundSerum sphingolipids are widely involved in the development of hepatocellular carcinoma (HCC). We investigated the serum sphingolipid profile in patients with HCC or cirrhosis and explored the potential diagnostic efficiency of serum ...
Yingying Jiang, Yingying Jiang, Cai Tie, Yang Wang, Yang Wang, Dandan Bian, Dandan Bian, Mei Liu, Mei Liu, Ting Wang, Ting Wang, Yan Ren, Yan Ren, Shuang Liu, Shuang Liu, Li Bai, Li Bai, Yu Chen, Yu Chen, Zhongping Duan, Zhongping Duan, Sujun Zheng, Sujun Zheng, Jinlan Zhang   +23 more
doaj   +1 more source

Negative impact of the pandemic on hospital admissions, morbidity and early mortality for acute cirrhosis decompensation

BMJ Open Gastroenterology, 2023
Introduction The global pandemic has diverted resources away from management of chronic diseases, including cirrhosis. While there is increasing knowledge on COVID-19 infection in liver cirrhosis, little is described on the impact of the pandemic on ...
Rajeshwar P Mookerjee, Kohilan Gananandan, Konstantin Kazankov, Alexandra Phillips, Hannah Old, Anmol Chikhlia, Ishrat Hussain, Sharmaine Jia Ying Sim, Niharika Thakur   +8 more
doaj   +1 more source

Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure. [PDF]

, 2009
Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure.
Borgulya, Gábor, Cervenak, László, Förhécz, Zsolt, Gombos, Tímea, Hársfalvi, Jolán, Jánoskuti, Lívia, Kunde, Jan, Makó, Veronika, Papassotiriou, Jana, Pozsonyi, Zoltán, Prohászka, Zoltán   +10 more
core   +1 more source

Mitochondrial Dysfunction in Advanced Liver Disease: Emerging Concepts

Frontiers in Molecular Biosciences, 2021
Mitochondria are entrusted with the challenging task of providing energy through the generation of ATP, the universal cellular currency, thereby being highly flexible to different acute and chronic nutrient demands of the cell.
Ingrid W. Zhang, Ingrid W. Zhang, Cristina López-Vicario, Cristina López-Vicario, Cristina López-Vicario, Marta Duran-Güell, Marta Duran-Güell, Joan Clària, Joan Clària, Joan Clària, Joan Clària   +10 more
doaj   +1 more source

Acute-on-chronic Liver Failure: MELD Score 30-day Mortality Predictability and Etiology in a Pakistani Population [PDF]

, 2020
Background: Cirrhosis is a pathological condition that ultimately leads to liver failure. Acute on chronic liver failure (ACLF) has a high short term mortality rate. Viral hepatitis is the most common cause of liver failure in our local population.
Gilani, N. A. (Naeem), Khalid, T. (Talha), Sarfraz, A. (Azza), Sarfraz, M. (Muzna), Sattar, S. (Saim), Siddiq, J. (Javaria)   +5 more
core