Results 21 to 30 of about 646,440 (257)

Mitochondrial Dysfunction in Advanced Liver Disease: Emerging Concepts

Frontiers in Molecular Biosciences, 2021
Mitochondria are entrusted with the challenging task of providing energy through the generation of ATP, the universal cellular currency, thereby being highly flexible to different acute and chronic nutrient demands of the cell.
Ingrid W. Zhang, Ingrid W. Zhang, Cristina López-Vicario, Cristina López-Vicario, Cristina López-Vicario, Marta Duran-Güell, Marta Duran-Güell, Joan Clària, Joan Clària, Joan Clària, Joan Clària   +10 more
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A dynamic prediction model for prognosis of acute-on-chronic liver failure based on the trend of clinical indicators

Scientific Reports, 2021
Acute-on-chronic liver failure (ACLF) is a dynamic syndrome, and sequential assessments can reflect its prognosis more accurately. Our aim was to build and validate a new scoring system to predict short-term prognosis using baseline and dynamic data in ...
Zhenjun Yu, Yu Zhang, Yingying Cao, Manman Xu, Shaoli You, Yu Chen, Bing Zhu, Ming Kong, Fangjiao Song, Shaojie Xin, Zhongping Duan, Tao Han   +11 more
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Association of Serum Bilirubin With Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis

Frontiers in Endocrinology, 2022
ObjectiveMetabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD) are the leading chronic diseases worldwide. There are still many controversies about the association between serum bilirubin and MetS or NAFLD.
Chen Liang, Chen Liang, Zhiyuan Yu, Zhiyuan Yu, Li Bai, Li Bai, Wei Hou, Shan Tang, Shan Tang, Wei Zhang, Xinyue Chen, Zhongjie Hu, Zhongping Duan, Zhongping Duan, Sujun Zheng   +14 more
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Characterization of Blood Immune Cells in Patients With Decompensated Cirrhosis Including ACLF

Frontiers in Immunology, 2021
Background and AimsPatients with cirrhosis and acute-on-chronic liver failure (ACLF) have immunosuppression, indicated by an increase in circulating immune-deficient monocytes.
Emmanuel Weiss, Emmanuel Weiss, Emmanuel Weiss, Pierre de la Grange, Mylène Defaye, Juan José Lozano, Ferrán Aguilar, Pushpa Hegde, Ariane Jolly, Lucile Moga, Lucile Moga, Sukriti Sukriti, Banwari Agarwal, Haqeeqat Gurm, Marion Tanguy, Johanne Poisson, Joan Clària, Joan Clària, Joan Clària, Joan Clària, Paer-Selim Abback, Axel Périanin, Gautam Mehta, Gautam Mehta, Gautam Mehta, Rajiv Jalan, Rajiv Jalan, Claire Francoz, Pierre-Emmanuel Rautou, Pierre-Emmanuel Rautou, Sophie Lotersztajn, Vicente Arroyo, François Durand, François Durand, Richard Moreau, Richard Moreau, Richard Moreau   +36 more
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Dysphagia to liver failure [PDF]

BMJ Case Reports, 2015
A 54-year-old man presenting with dysphagia, weight loss, epigastric pain and cervical lymphadenopathy was referred directly to endoscopy. The medical history included hypertension and hypercholesterolaemia. Blood tests showed normal bilirubin, aspartate transaminase (AST) 490 iu/L, γ-glutamyl transferase (GGT) 535 iu/L, alkaline phosphatase (ALP) 829 ...
Vincent Ting Fung, Cheung, Jey, Singanayagam, Angus, Molyneux, Neil, Rajoriya   +3 more
openaire   +2 more sources

Systemic Inflammation and Acute-on-Chronic Liver Failure: Too Much, Not Enough

Canadian Journal of Gastroenterology and Hepatology, 2018
ACLF is a specific, but complex and multifactorial form of acute decompensation of cirrhosis and is characterized by an extraordinary dynamic natural course, rapidly evolving organ failure, and high short-term mortality.
Wim Laleman, Joan Claria, Schalk Van der Merwe, Richard Moreau, Jonel Trebicka   +4 more
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The neurology of liver failure [PDF]

QJM, 2003
That there is a relationship between the brain and the liver has been known for many years,1 and patients with chronic liver disease frequently experience neurological problems. The commonest and most widely recognized is the reversible syndrome of hepatic encephalopathy,2 and we will deal with this in some detail.
M, Lewis, P D, Howdle
openaire   +2 more sources

Usefulness of serum thyroid-stimulation hormone (TSH) as a prognostic indicator for acute-on-chronic liver failure

Annals of Hepatology, 2015
Background and rationale for the study. To investigate thyroid function in patients with acute-on-chronic liver failure (ACLF) caused by hepatitis B virus infection and to determine whether thyroid hormone levels can be used as prognostic markers for ...
Yichen Wu, Shaoli You, Hong Zang, Hongling Liu, Yuanli Mao, Panyong Mao, Bing Zhu, Jun Xu, Guoming Xie, Jingxia Guo, Dongze Li, Shaojie Xin, Zhihong Wan   +12 more
doaj   +1 more source

Age-specific reference values for low psoas muscle index at the L3 vertebra level in healthy populations: A multicenter study

Frontiers in Nutrition, 2022
Background and aimsThe progressive and generalized loss of skeletal muscle mass, strength and physical function is defined as sarcopenia. Sarcopenia is closely related to the prognosis of patients. Accurate diagnosis and adequate management of sarcopenia
Ming Kong, Ning Lin, Lili Wang, Nan Geng, Manman Xu, Shanshan Li, Wenyan Song, Ying Zhou, Yuetong Piao, Zuoqing Han, Rong Guo, Chao Yang, Nan Luo, Zhong Wang, Quanxiao Xu, Daimeng Shi, Wanchun Qiu, Junfeng Li, Eddie C. Cheung, Eddie C. Cheung, Lei Ma, Yu Chen, Zhongping Duan   +22 more
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Prospective multicentre randomised controlled trial to assess the clinical effectiveness of the novel CirrhoCare digital therapeutic management system: a study protocol

BMJ Open
Introduction Liver cirrhosis accounts for over 10 000 deaths in the UK each year with a total loss of 60 000 quality-adjusted life-years. There is a substantial cost to the NHS of £4.5 billion, with new liver-related decompensation events accounting for ...
Rajeshwar P Mookerjee, Rajiv Jalan, Olivia Greenham, Kohilan Gananandan, Zia Sadique, Konstantin Kazankov, RAVI KUMAR, Anu Balaji, Maruthi Raja, Ravan Boddu, Jonathan Bamber, Karen L Thomsen, Jenny Philip, Anvi Wadke   +13 more
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