Results 11 to 20 of about 646,440 (257)

Psoas Muscle Index Can Be Used to Predict Long-Term Mortality in Young Male Patients With Acute-on-Chronic Liver Failure

open access: yesFrontiers in Nutrition, 2022
ObjectiveThe use of psoas muscle index (PMI) in acute-on-chronic liver failure (ACLF) has not been reported, and the aim of this study was to evaluate the predictive value of PMI for the prognosis of patients with ACLF.MethodsIn this study, male ACLF ...
Manman Xu   +13 more
doaj   +1 more source

Acute liver failure [PDF]

open access: yesClinical Medicine, 2011
ALF is a multisystem disorder necessitating both predictive and reactive management strategies to support and protect organs from the initial and subsequent insults encountered. Early referral to a specialist liver centre with the option of liver transplantation is recommended.
Andy, Slack, Julia, Wendon
openaire   +4 more sources

High-dependency units play a key role in the treatment of a Chinese military patient who developed liver failure while abroad

open access: yesMilitary Medical Research, 2019
High-dependency units (HDUs) provide high-level care to patients who suffer from single organ failure, with the exception of respiratory failure requiring mechanical ventilation; HDUs serve as an intermediary between general wards and Intensive Care ...
Chen Li   +4 more
doaj   +1 more source

Combined Effects of UGT1A1 and SLCO1B1 Variants on Chinese Adult Mild Unconjugated Hyperbilirubinemia

open access: yesFrontiers in Genetics, 2019
The potential for genetic variation to cause adult unconjugated hyperbilirubinemia is increasingly being recognized. However, the cumulative effects of genetic variants have not been fully illuminated.
Jie Bai   +12 more
doaj   +1 more source

Kuhuang injection exerts a protective effect by activating PPAR-γ in an in vitro model of chlorpromazine-induced cholestatic liver injury constructed by tissue engineering

open access: yesPharmaceutical Biology, 2022
Context Kuhuang (KH) injection is a widely used anticholestatic drug in the clinic and the mechanisms are still unclear.Objective This study uses a new 3D tissue-engineered (TE) liver platform to study the ability of kuhuang to ameliorate liver injury ...
Qiao Wu   +3 more
doaj   +1 more source

Post-Transcriptional Regulation of Hepatic DDAH1 with TNF Blockade Leads to Improved eNOS Function and Reduced Portal Pressure In Cirrhotic Rats

open access: yesScientific Reports, 2017
Portal hypertension (PH) is a major cause of morbidity and mortality in chronic liver disease. Infection and inflammation play a role in potentiating PH and pro-inflammatory cytokines, including TNF, are associated with severity of PH.
V. Balasubramanian   +6 more
doaj   +1 more source

Acute Liver Failure [PDF]

open access: yesSeminars in Respiratory and Critical Care Medicine, 1993
Acute liver failure (ALF) (sometimes referred to as fulminant hepatic failure) is a clinical syndrome from a variety of causes resulting from rapid loss in hepatocyte function, typically associated with coagulopathy and encephalopathy in a patient without preexisting liver disease or cirrhosis. Cerebral edema is a cardinal feature and may produce uncal
openaire   +4 more sources

Upregulation of Serum Sphingosine (d18:1)-1-P Potentially Contributes to Distinguish HCC Including AFP-Negative HCC From Cirrhosis

open access: yesFrontiers in Oncology, 2020
BackgroundSerum sphingolipids are widely involved in the development of hepatocellular carcinoma (HCC). We investigated the serum sphingolipid profile in patients with HCC or cirrhosis and explored the potential diagnostic efficiency of serum ...
Yingying Jiang   +23 more
doaj   +1 more source

Infection deteriorating hepatitis B virus related acute-on-chronic liver failure: a retrospective cohort study

open access: yesBMC Gastroenterology, 2020
Background Infection is common in acute-on-chronic liver failure (ACLF), which may worsen the clinical condition and prognosis. However, the characteristics of infection and its influence on prognosis in hepatitis B virus related ACLF (HBV-ACLF) as ...
Xing-Ran Zhai   +9 more
doaj   +1 more source

Negative impact of the pandemic on hospital admissions, morbidity and early mortality for acute cirrhosis decompensation

open access: yesBMJ Open Gastroenterology, 2023
Introduction The global pandemic has diverted resources away from management of chronic diseases, including cirrhosis. While there is increasing knowledge on COVID-19 infection in liver cirrhosis, little is described on the impact of the pandemic on ...
Rajeshwar P Mookerjee   +8 more
doaj   +1 more source

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