Results 101 to 110 of about 12,928,896 (364)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Probiotics are beneficial for liver cirrhosis: a systematic review and meta-analysis of randomized control trials

Frontiers in Medicine
IntroductionGut dysbiosis may play a pivotal role in the pathogenesis of cirrhosis and the severity of complications. Numerous studies have investigated the probiotics as treatments for cirrhosis.
Xing Yang, Langhuan Lei, Wei Shi, Xiaozhen Li, Xiaozhi Huang, Liuyan Lan, Jiali Lin, Qiuyu Liang, Wei Li, Jianrong Yang   +9 more
doaj   +1 more source

ON THE FUNCTION AND DISEASES OF THE LIVER. [PDF]

The Lancet
n ...
openaire   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Effects of l‐carnitine on frailty status in patients with liver cirrhosis: A randomized‐controlled trial

Health Science Reports
Background and Aims Frailty is a common complication in patients with liver cirrhosis, which is linked with augmented rates of morbidity and mortality. In this regard, timely nutritional assessment and intervention have gained scientific attention.
Nasrin Motazedian, Anita Ashari, Niloofar Dehdari Ebrahimi, Mehrab Sayadi, Sarina Pourjafar, Nazanin Motazedian, Vahid Khademi, Alireza Shamsaeefar, Ahad Eshraghian   +8 more
doaj   +1 more source

Lipoprotein(a) as a potential marker of residual liver function in hepatocellular carcinoma

Indian Journal of Medical and Paediatric Oncology, 2011
The residual liver function is a major clinical index in hepatocellular carcinoma (HCC) patients. As the liver plays a crucial role in lipid and lipoprotein metabolism, the significant impairment of the hepatic function occurring during chronic liver ...
Mario Uccello, Giulia Malaguarnera, Elisa M Pelligra, Antonio Biondi, Francesco Basile, Massimo Motta   +5 more
doaj   +1 more source

STUDIES IN LIVER AND KIDNEY FUNCTION IN EXPERIMENTAL PHOSPHORUS AND CHLOROFORM POISONING [PDF]

, 1915
E. K. Marshall, Leonard G. Rowntree
openalex   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

AN INVESTIGATION INTO THE EFFECTS OF THE ARSENOBENZOL TREATMENT OF SYPHILIS ON LIVER FUNCTION [PDF]

, 1923
H. MacCormac, E. C. Dodds
openalex   +1 more source