Results 121 to 130 of about 527,738 (310)
Liver function tests in children with blunt abdominal traumas
, 2007 Previous studies have suggested that there are cut-off values for liver function tests (LFTs) beneath which significant liver injury can be excluded after blunt abdominal trauma in children.
Le Coultre, Claude Pierrette +3 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
, 2009 The last decade has seen an explosion of activity in the clinical and research aspects of pediatric hepatology. The increased use of ultrasounds techniques and routine laboratory evaluation has drawn attention to several previously undiagnosed condition ...
Caropreso, Maria
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
International Journal of General MedicineAbdifatah Abdullahi Jalei,1 Abdifetah Ibrahim Omar,1,2 Shafie Abdulkadir Hassan,1 Yahye Sheikh Abdulle Hassan,1 Nur Rashid Ahmed1,2 1Faculty of Medicine and Health Sciences, Jamhuriya University of Science and Technology, Mogadishu, Somalia; 2Jamhuriya ...
Jalei AA +4 more
doaj
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017 BACKGROUND AND OBJECTIVE: Considering the fact that oral feeding is delayed too much in extremely premature infants due to respiratory and digestive problems, these infants usually suffer from severe weight loss and muscular dystrophy in the absence of ...
S Aramli +3 more
doaj
Autonomic and sensory nerve dysfunction in primary biliary cirrhosis
, 2004 AIM: Cardiovascular autonomic and peripheral sensory neuropathy is a known complication of chronic alcoholic and non-alcoholic liver diseases. We aimed to assess the prevalence and risk factors for peripheral sensory nerve and autonomic dysfunction using
Horváth, Andrea +8 more
core
Study of abnormal liver function tests in pregnancy in a tertiary centre in North Kerala
, 2017 Background: Abnormal liver function tests in pregnancy require proper evaluation and diagnosis. The underlying disorder can have a significant effect on the outcome of both mother and fetus.
Simi Kurian +3 more
core +1 more source