Results 51 to 60 of about 544,396 (267)

Thyroid Profile in Patients of Cirrhosis of Liver: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Liver plays an important role in the metabolism of thyroid hormones. It also has a dominant role in the production and secretion of thyroid binding globulin.
Sudhir Kumar Verma, Vivek Kumar, Pradyot Tiwari, Nikhil Kumar P Joge, Ravi Misra   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Evaluation of Some Liver Function Tests in Clinical Cases of Hepatic Insufficiency in Buffaloes

Italian Journal of Animal Science, 2010
The investigation was conducted on 35 clinical cases of hepatic insufficiency in buffaloes. The cases for study were selected on the basis of clinical symptoms and results of liver function tests. All these cases were anorectic and non-febrile.
S. Sridhar, V. Sharma
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Evaluation of the Liver and Pancreatic Functions in Patients with Alcohol-Related Sialadenosis – A Case Control Study

Journal of Pharmacy and Bioallied Sciences
Background: Sialadenosis or sialosis is the asymptomatic symmetric parotid enlargement without inflammation or neoplasia, seen in persons 30–69 years old, often related to chronic alcohol use, endocrine disorders, and obesity. Materials and Methods: This
E Elavarasi, Vinothini Gunasekaran, Mohan Thirumal, R Balaji Subramaniyan, Ravi David Austin, S Thirumalai   +5 more
doaj   +1 more source

Correlation between liver function tests and metabolic syndrome in hepatitis-free elderly

Journal of Medical Sciences, 2015
Background: We aimed to investigate the relationship between liver function tests (LFTs) and metabolic syndrome (MetS) as several studies have shown positive correlations between some of the LFTs, including alanine aminotransferase (ALT) and γ-glutamyl ...
Hung-Sheng Shang, Bing-Heng Yang, Cherng-Lih Perng, Sheng-Hue Tang, Chien-Ming Lin, Jin-Biou Chang   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source