Results 161 to 170 of about 4,187,942 (381)
Mechanisms of Alcoholic Liver Injury [PDF]
Canadian Journal of Gastroenterology, 2000 There have been numerous recent advances in the understanding of the mechanisms of alcoholic liver disease pathogenesis. Endotoxin-induced Kupffer cell activation plays a role in cytokine-mediated inflammatory changes in the liver, and this can be blocked by a diet high in saturated fat, by a diet containing lactobacillus, which does not produce ...
openaire +3 more sources
Arthritis Care &Research, Accepted Article.Objectives Australian evidence on lived and care experiences of chronic musculoskeletal shoulder pain (CMSP), irrespective of disorder classification or disease, is limited. However, such evidence is important for person‐centred care and informing local service pathways and care guidelines or standards.
Sonia Ranelli +8 more
wiley +1 more source
Assessment of serum bile acid profiles as biomarkers of liver injury and liver disease in humans
PLoS ONE, 2018 To assess the potential of individual bile acids (IBA) and their profiles as mechanistic biomarkers of liver injury for humans in real world situations, we interrogated samples collected under minimum controlled conditions (ie subjects were not fasted ...
Lina Luo +6 more
semanticscholar +1 more source
Advanced Biology, EarlyView.Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe +4 more
wiley +1 more source
Liver injury in COVID-19: management and challenges
The Lancet Gastroenterology and Hepatology, 2020 Chao Zhang, Lei Shi, Fu-Sheng Wang
semanticscholar +1 more source
American Journal of Physiology - Gastrointestinal and Liver Physiology, 2019 Tumor necrosis factor-α (TNF-α) is a highly pleiotropic cytokine executing biological functions as diverse as cell proliferation, metabolic activation, inflammatory responses, and cell death.
Zhen-Tang Jing +6 more
semanticscholar +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Evidence for hyperacute rejection of human liver grafts: The case of the canary kidneys [PDF]
, 1989 Sequential liver and kidney transplantation from the same donor was performed in 2 patients. The kidney in Patient 1, which was transplanted after the liver, was hyperacutely rejected and removed 6 hours later.
Banner, B +9 more
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Toxic liver injury. The metabolism of dimethylnitrosamine in vitro [PDF]
, 1958 Peter Magee, M. Vandekar
openalex +1 more source
Role of macrophages in experimental liver injury and repair in mice.
Experimental and Therapeutic Medicine, 2019 Liver macrophages make up the largest proportion of tissue macrophages in the host and consist of two dissimilar groups: Kupffer cells (KCs) and monocyte-derived macrophages (MoMø).
Xiaotian Dong +3 more
semanticscholar +1 more source