Results 181 to 190 of about 452,276 (305)

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

open access: yesAdvanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu   +5 more
wiley   +1 more source

TRAP-seq identifies cystine/glutamate antiporter as a driver of recovery from liver injury

open access: green, 2018
Amber W. Wang   +6 more
openalex   +2 more sources

Severe acute liver injury in patients with exertional heat stroke associated with poor short-term prognosis [PDF]

open access: bronze, 2022
Chen Li   +6 more
openalex   +1 more source

Calcium Imparts Advanced Functionalities to Silk Hydrogels for Biofabrication and Biomedical Innovation

open access: yesAdvanced Functional Materials, EarlyView.
The addition of calcium ions to silk fibroin enhances the hydrogel properties and, when combined with visible light crosslinking, enables compatibility with advanced light‐based fabrication techniques. Calcium ions extend the shelf‐life of silk and facilitate the fabrication of multizonal, multilayered constructs for advanced stimuli‐responsive ...
Hien A. Tran   +11 more
wiley   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Matrix Remodeling Associated 7 Deficiency Alleviates Carbon Tetrachloride-Induced Acute Liver Injury in Mice

open access: gold, 2018
Dandan Lin   +8 more
openalex   +1 more source

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

open access: yesAdvanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao   +9 more
wiley   +1 more source

The Synergy of Artificial Intelligence and 3D Bioprinting: Unlocking New Frontiers in Precision and Tissue Fabrication

open access: yesAdvanced Functional Materials, EarlyView.
Advances in integrating artificial intelligence into 3D bioprinting are systematically reviewed here. Machine learning, computer vision, robotics, natural language processing, and expert systems are examined for their roles in optimizing bioprinting parameters, real‐time monitoring, quality control, and predictive maintenance.
Joao Vitor Silva Robazzi   +10 more
wiley   +1 more source

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