Results 251 to 260 of about 864,474 (360)

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

open access: yesAdvanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu   +4 more
wiley   +1 more source

Hydrogel‐Impregnated Robust Interlocking Nano Connector (HiRINC) for Noninvasive Anti‐Migration of Esophageal Stent

open access: yesAdvanced Materials, EarlyView.
The development of hydrogel‐impregnated robust interlocking nano connector (HiRINC) aims to address stent migration by improving tissue adhesion and reducing mechanical mismatch in self‐expandable metallic stents (SEMSs). The network‐like porous layer of HiRINC enhances adhesion and energy dissipation, demonstrates through ex vivo and in vivo tests ...
Eunyoung Jeon   +8 more
wiley   +1 more source

TAK-994 mechanistic investigation into drug-induced liver injury. [PDF]

open access: yesToxicol Sci
Shinozawa T   +17 more
europepmc   +1 more source

Recent Advances in Stimuli‐Responsive Materials and Soft Robotic Actuators for Bioelectronic Medicine

open access: yesAdvanced Materials, EarlyView.
This review explores the integration of responsive materials and soft robotic actuators with implantable electronics to address key challenges in bioelectronic medicine. By enabling shape actuation, these technologies improve deployment, adaptability, and accuracy in minimally invasive procedures.
Chaoqun Dong, George G. Malliaras
wiley   +1 more source

High levels of acetaldehyde in nonalcoholic liver injury after threonine or ethanol administration [PDF]

open access: bronze, 1989
Xiaoli Ma   +3 more
openalex   +1 more source

Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction

open access: yesAdvanced Materials, EarlyView.
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang   +12 more
wiley   +1 more source

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