Results 91 to 100 of about 2,212,278 (393)

Undifferentiated embryonal sarcoma of the liver in elderly: Case report and review of the literature

Indian Journal of Pathology and Microbiology, 2019
Sarcomas are rare lesions of the liver and represent
Gunter Gerson, José Telmo Valença, Juliana M Cavalcante, River De Alencar Bandeira Coêlho   +3 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

An Enlarging Metastatic Calcified Liver Lesion of an Occult Melanoma

Case Reports in Oncology, 2018
Calcified liver lesions are caused by a wide variety of factors. The most common lesions are inflammatory liver lesions followed by benign and malignant neoplasms.
Mohamad A. Mouchli, Sarah E. Kerr, Lewis Roberts   +2 more
doaj   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Serous cystic neoplasm of the pancreas: A multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas) [PDF]

, 2015
OBJECTIVES: Serous cystic neoplasm (SCN) is a cystic neoplasm of the pancreas whose natural history is poorly known. The purpose of the study was to attempt to describe the natural history of SCN, including the specific mortality.
Aguero Garcete, G., Angiolini, M. R., Araujo Acuna, I., Arcidiacono, P. G., Balzano, G., Bassi, C., Bernier, B., Bissolati, M., Bolado, F., Brugge, W., Campos, V., Casadei, R., Choi, H. J., Concepcion Martin, M., Conwell, D., Crippa, S., De Angelis, C. G., Del Chiaro, M., Delhaye, M., Faccinetto, A., Falconi, M., Fern\ue1ndez Del Castillo, C., Fontana, M., Frigerio, I., Frulloni, L., Gill, R. S., Girelli, R., Gomatos, I., Ha, Y., Hirai, I., Hruban, R., Huggett, M. T., Ikeura, T., Jais, B., Jang, J. Y., Jang, K. T., Jung, W., Kang, C. M., Kang, H., Keane, M. G., Kim, M. H., Kim, S. W., Kimura, W., Kopchak, K. V., L\ue9vy, P., Lee, L. S., Lee, W. J., Lennon, A. M., Leong, R. W., Maggino, L., Malleo, G., Manfredi, R., Marchegiani, G., Matsumoto, I., Messina, O., Milanetto, Anna Caterina, Moon, J. H., Moran, R., Morana, G., Napoleon, B., Neoptolemos, J., Oh, D., Okazaki, K., Oppong, K. W., Osvaldt, A., Oua\uefssi, M., Pavey, D., Pereira, S. P., Pererva, L., Petrone, M. C., Rebours, V., Ricci, C., Rios Vives, M. A., Salvia, R., Sastre, B., Segersvard, R., Shinzeki, M., Song, D. H., Song, S. Y., Spandre, M., Sperti, Cosimo, Tang, J., Urman Fernandez, J. M., Vaquero, E. C., Wang, H., Wolfgang, C., Zaheer, A., Zerbi, A.   +87 more
core   +2 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S., Allolio, B., Beuschlein, Felix, Chrousos, G. P., Jaursch-Hancke, C., Karl, M., Reincke, Martin, Travis, W.   +7 more
core  

Multiple inflammatory pseudotumors of the liver and spleen

Journal of the Belgian Society of Radiology, 2010
Background: A 43-year-old woman presented with periods of fever of 4 weeks duration, epigastric pain and significant loss of weight (16 kg). Laboratory findings revealed elevated C-reactive protein and slightly elevated liver function tests.
E Bruyeer, K Ramboer
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source