Results 81 to 90 of about 617,178 (314)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Surgical Management Of Liver Metastases From Uveal Melanoma

Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2015
Melanomas are malignant neoplasms of melanocytes developing predominantly in the skin, but occasionally arising from eyes, mucous membranes, and the central nervous system. Uveal melanoma is the most common primary intraocular malignancy in adults.
Ulaș Sözener, Tevfik Eker, Sadık Ersöz   +2 more
doaj   +1 more source

Biliary papillary neoplasm of the liver.

Histology and histopathology, 2002
Biliary papillary neoplasia of the liver characterized by intraductal papillary growth of neoplastic biliary epithelia with a fine fibrovascular stalk has been sporadically reported, and includes intraductal growing cholangiocarcinoma and biliary papillomatosis.
Nakanuma, Y., Sasaki, M., Ishikawa, A., Tsui, W., Chen, T.C., Huang, S.F.   +5 more
openaire   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Laparoscopic large liver resections for benign focal neoplasms

Український журнал клінічної хірургії
Objective. To evaluate the safety, intraoperative features, and early postoperative results of laparoscopic major liver resections for benign focal neoplasms. Materials and methods.
D. O. Fedorov, O. O. Pidopryhora, O. M. Ostapyshen   +2 more
doaj   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S., Allolio, B., Beuschlein, Felix, Chrousos, G. P., Jaursch-Hancke, C., Karl, M., Reincke, Martin, Travis, W.   +7 more
core  

Thymoma metastatic to liver and pancreas: case report and review of the literature [PDF]

, 2017
A 71-year-old man presented with a thymic mass involving the superior vena cava. A mediastinoscopical biopsy initially suggested a diagnosis of type A thymoma.
Blandamura, Stella, Passuello, Nicola, Pozza, Gioia, Sperti, Cosimo, Valmasoni, Michele   +4 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Incidence of hepatocellular carcinoma in hepatitis C cirrhotic patients with and without HIV infection: a cohort study, 1999-2011

Annals of Hepatology, 2014
Introduction. High activity antiretroviral therapy (HAART) has allowed people infected with human immunodeficiency virus (HIV) to live longer. In the course of time, hepatocellular carcinoma (HCC) began to be found in these patients.
Nicolas Di Benedetto, Mirta Peralta, Estela Alvarez, María Teresa Schroder, Claudio Estepo, Silvia Paz, Hugo Fainboim   +6 more
doaj   +1 more source

The burden of premature mortality in Poland analysed with the use of standard expected years of life lost [PDF]

, 2015
Background: Despite positive changes in the health of the population of Poland, compared to the EU average, the average life expectancy in 2011 was 5 years shorter for males and 2.2 years shorter for females.
Bryła, Marek, Bryła, Paweł, Maniecka-Bryła, Irena, Pikala, Małgorzata   +3 more
core   +2 more sources