Human organoids and organ-on-chip systems for AI-guided therapeutic discovery against emerging and re-emerging infections. [PDF]
Makkar SK, Bhatia S, Nguyen N, Wei G.
europepmc +1 more source
A chemically optimized, GalNAc-conjugated siRNA targeting HSD17B13 demonstrates efficacy in a human 3D organoid model of MASH, showcasing an alternative to animal testing. [PDF]
Meng Q +6 more
europepmc +1 more source
An Immunocompetent Hepatic Organoid Model Reveals Conserved Hepatic Immune Dysregulation During <i>Leishmania donovani</i> Infection. [PDF]
González-Montero MC +6 more
europepmc +1 more source
Integration of biological avatars and digital twins for "ex vivo clinical trials". [PDF]
Howe CL.
europepmc +1 more source
Stem Cell Models for Elucidating Cellular Mechanisms of Substance Use Disorders and Advancing Addiction Pharmacology. [PDF]
Koo JS, Zhang H.
europepmc +1 more source
Harnessing human tumor organoids for cancer modeling and precision therapy. [PDF]
Zhou T, Wang Q, Zhang M, Huang Y.
europepmc +1 more source
Biobanked Liver Organoids: A Roadmap for Precision Hepatology. [PDF]
Cabré EJ +5 more
europepmc +1 more source
Engineering Organoid Platforms for Pathogenesis Research. [PDF]
Han X +6 more
europepmc +1 more source

