Results 101 to 110 of about 327,334 (304)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Treatment of hepatic epithelioid hemangioendothelioma with liver transplantation [PDF]

, 1988
Ten patients received liver transplants for unresectable epithelioid hemangioendothelioma (EHE). At the time of transplantation, four patients had microscopic metastases to the hilar lymph nodes, and one of the four also had metastases to a rib.
Esquivel, CO, Iwatsuki, S, Kelleher, M, Klintmalm, G, Marino, IR, Starzl, TE, Todo, S, Tzakis, MG   +7 more
core   +1 more source

Glutathione and Laccase Dual‐Responsive Lignin Nanocarriers Inspired by Host‐Pathogen Interactions for Fungicide Delivery

Advanced Functional Materials, EarlyView.
Discover bio‐inspired fungicide‐loaded lignin nanocarriers that mimic host‐pathogen interactions, unleashing targeted fungicide release in response to glutathione and laccase. These innovative biobased nanocarriers promise superior crop protection, with increased photostability, enhanced foliar retention, and enabling bidirectional translocation for a ...
Wenlong Liang, Jingli Cheng, Lianmeng Liu, Jinhao Zhao, Frederik R. Wurm   +4 more
wiley   +1 more source

Identification of glycolysis-related molecular subtypes and prognostic model in intrahepatic cholangiocarcinoma

Discover Oncology
Background Intrahepatic cholangiocarcinoma (iCCA) is the second most common primary liver tumor, notable for its high heterogeneity. Glycolysis plays a critical role in tumorigenesis, progression, and drug resistance across various malignancies, while ...
Yue Wang, Pengxiang Wang, Hui Liu, Haokang Feng, Muzi Cao, Zefan Zhang, Keqiang Rao, Jia Fan, Xiutao Fu, Yunfan Sun   +9 more
doaj   +1 more source

Dual graft living donor liver transplantation – a case report

BMC Surgery, 2019
Background Living donor liver transplantation (LDLT) has emerged as an equally viable option to deceased donor liver transplant for treating end stage liver disease patients.
Nikam Vinayak, Mohanka Ravi, Golhar Ankush, Bhade Rashmi, Rao Prashantha, Gadre Parul, Shrimal Anurag   +6 more
doaj   +1 more source

Protocol TOP-Study (tacrolimus organ perfusion): a prospective randomized multicenter trial to reduce ischemia reperfusion injury in transplantation of marginal liver grafts with an "ex vivo" tacrolimus perfusion [PDF]

, 2013
Background: Critical organ shortage results in the utilization of extended donor criteria (EDC) liver grafts. These marginal liver grafts are prone to increased ischemia reperfusion injury (IRI) which may contribute to deteriorated graft function and ...
Angele, Martin Kurt, Eder, Michael, Heise, Michael, Jauch, Karl-Walter, Nadalin, Silvio, Pascher, Andreas, Pratschke, Sebastian, Schemmer, Peter, Scherer, Marcus N., Ulrich, Frank, Wolters, Heiner, Wöhling, Dirk   +11 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Engineering Highly Cellularized Living Materials via Mechanical Agitation

Advanced Functional Materials, EarlyView.
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani, Shiyu Liu, Evan Johnston, Weiyi Wan, Xiaoyi Lan, Tianqin Ning, Alexander Nottegar, Ran Huo, Shuaibing Jiang, Jianyu Li   +9 more
wiley   +1 more source

Rotational thormboelastolmetry guided transfusion practice in living donor liver transplantation, A retrospective comparative study

Egyptian Journal of Anaesthesia, 2018
Introduction: Living donor liver transplantation (LDLT) is a complex surgery with high risk for massive bleeding and blood component transfusion. This retrospective study investigated the effect of adopting ROTEM based transfusion algorithm on blood ...
Al-Refaey Kandeel, Usama Abdalla, Mohamed Abouelella, Mohammed Elmorshedi, Waleed Elsarraf, Mohammed Abdelwahab, Amr Yassen   +6 more
doaj   +1 more source

A new liver perfusion and preservation system for transplantation Research in large animals [PDF]

, 1990
A kidney perfusion machine, model MOX-100 (Waters Instruments, Ltd, Rochester, MN) was modified to allow continuous perfusion of the portal vein and pulsatile perfusion of the hepatic artery of the liver. Additional apparatus consists of a cooling system,
A. Jake Demetris, Belzer F O, Denmark S W, Greenway C V, Guy Lebeau, Hoffmann R M, Jamieson N V, Katsuhiko Yanaga, Leonard Makowka, Mitsuo Shimada, Moore F D, Ruey Rong Hwang, Saburo Kakizoe, Starzl T E, Starzl T E, Starzl T E, Thomas E. Starzl, Williams J W   +17 more
core   +1 more source