Results 101 to 110 of about 2,986,927 (385)

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Machine-Learning Algorithms Predict Graft Failure After Liver Transplantation

open access: yesTransplantation, 2017
Background The ability to predict graft failure or primary nonfunction at liver transplant decision time assists utilization of scarce resource of donor livers, while ensuring that patients who are urgently requiring a liver transplant are prioritized ...
Lawrence F. Lau   +6 more
semanticscholar   +1 more source

Age and liver transplantation [PDF]

open access: yesJournal of Hepatology, 2019
The average age of liver transplant donors and recipients has increased over the years. Independent of the cause of liver disease, older candidates have more comorbidities, higher waitlist mortality and higher post-transplant mortality than younger patients.
François Durand   +7 more
openaire   +5 more sources

Liver Transplantation for Alagille's Syndrome [PDF]

open access: yes, 1993
Twenty-three children with Alagille's syndrome and end-stage liver disease underwent liver transplantation with cyclosporine and low-dose steroid immunosuppression. Two to 9 years (mean, 4.4 years) after surgery, 13 (57%) of the children were still alive,
Reyes, J   +5 more
core   +1 more source

Living Related Donor Liver Transplantation with Atrio- Caval Anastomosis of Inferior Vena Cava Graft Stored in Deep-Freeze for Budd-Chiari Syndrome

open access: yesInternational Journal of Organ Transplantation Medicine, 2015
We have previously reported our experience in inferior vena cava resection and reconstruction techniques during liver transplantation for Budd-Chiari syndrome.
F Yaylak   +5 more
doaj  

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

Split Liver Transplantation

open access: yes, 2016
Liver transplantation is the most effective treatment for the patients with acute liver failure or end-stage liver diseases. Liver transplantation is also indicated for patients with hepatocellular carcinoma to yield a best result if the tumor/tumors ...
Wei-Chen Lee
semanticscholar   +1 more source

The Long‐Term Benefit of Liver Transplantation for Hepatic Metastases From Neuroendocrine Tumors

open access: yesAmerican Journal of Transplantation, 2016
Selection criteria and benefit of liver transplantation for hepatic metastases from neuroendocrine tumors (NETs) remain uncertain. Eighty‐eight consecutive patients with metastatic NETs eligible for liver transplantation according to Milan‐NET criteria ...
Vincenzo Mazzaferro   +14 more
semanticscholar   +1 more source

Adult liver transplantation: An analysis of the early causes of death in 40 consecutive cases [PDF]

open access: yes, 1986
One hundred twenty‐nine adult patients who received an orthotopic liver transplantation and survived at least 24 hr after surgery were evaluated. During the period of follow‐up, 48 of the 129 patients (37%) died.
Calne   +17 more
core   +1 more source

Radiotherapy medical physics in the Philippines: A contemporary overview

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose With cancer ranking as the third leading cause of death in the Philippines and a disparity in healthcare resources across regions, this research aimed to assess the state of radiotherapy medical physics in the country. Methodology The study utilized a comprehensive online survey with 94 structured questions answered by 19 clinics ...
John Paul C. Cabahug   +4 more
wiley   +1 more source

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