Results 81 to 90 of about 1,150,856 (250)

Association of Pretransplant Renal Function With Liver Graft and Patient Survival After Liver Transplantation in Patients With Nonalcoholic Steatohepatitis [PDF]

, 2019
Background: Nonalcoholic Steatohepatitis(NASH) is one of the top three indications for liver transplantation in western countries. It is unknown whether renal dysfunction at the time of liver transplantation has any effect on post-liver transplantation ...
Satheesh Nair, Aithal, Guruprasad Padur, Bhamidimarri, Kalyan Ram, Eason, James D, Joglekar, Kiran, Duseja, Ajay, Satapathy, Sanjaya K., Vincent Wai‐Sun Wong, Aijaz Ahmed, Ahmed, Aijaz, Yu Jiang, Gonzalez, Humberto C, George Cholankeril, Singal, Ashwani, Ashwani Singal, Jiang, Yu, Wong, Vincent Wai-Sun, Mubeen Khan Mohammed Abdul, Nair, Sathees, Kiran Joglekar, Puneet Puri, Satapathy, Sanjaya K, Miklos Z. Molnar, Sanjaya K. Satapathy, Kedia, Satish, Puri, Puneet, Eason, James D., Satish Kedia, Agayeva Gulnare, Cholankeril, George, Abdul, Mubeen Khan Mohammed, Molnar, Miklos Z., Gulnare, Agayeva, James D. Eason, Wong, Vincent Wai‐Sun, Ajay Duseja, Nair, Satheesh, Molnar, Miklos Z, Guruprasad Padur Aithal, Humberto C. Gonzalez, Kalyan Ram Bhamidimarri, Gonzalez, Humberto C., Wong, Vincent Wai Sun   +42 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Different aprotinin applications influencing hemostatic chances in orthotopic liver transplantation [PDF]

, 1992
The effect of different aprotinin applications on hemmtatic changes and blood product requirements in orthotopic liver transplantation was investigated in a prospective, open, and randomized study.
Bechstein, W. O., Muser, M., Neuhaus, P., Himmelreich, G., Jochum, Marianne, Riess, H., Slama, K.-J.   +6 more
core   +1 more source

Temporary Parenteral Tacrolimus Requirement due to Unexplained Low Through Levels in a Liver Transplant Patient with Short Bowel Syndrome

International Journal of Organ Transplantation Medicine, 2014
An adequate level of tacrolimus in serum should be obtained to prevent acute rejection following liver transplantation. Because of good gastrointestinal absorption of oral tacrolimus, adequate trough levels can be achieved even in patients with short ...
V Ince, F Ozdemir, B Isik, M Yilmaz, C Kayaalp, S Yilmaz   +5 more
doaj  

Long-Term Outcome Following Liver Transplantation for Primary Hepatic Tumors—A Single Centre Observational Study over 40 Years

, 2023
The incidence of pediatric liver tumors in general has been rising over the last years and so is the number of children undergoing liver transplantation for this indication.
Mutschler, Frauke E., Junge, Norman; 2Pediatric Gastroenterology, Hepatology and Liver Transplantation, Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany, Mutschler, Frauke E.; 2Pediatric Gastroenterology, Hepatology and Liver Transplantation, Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany, Vondran, Florian W. R.; 3Department of General, Visceral and Transplant Surgery, Hannover Medical School, 30625 Hannover, Germany, Baumann, Ulrich; 2Pediatric Gastroenterology, Hepatology and Liver Transplantation, Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany, Pfister, Eva-Doreen, Pfister, Eva-Doreen; 2Pediatric Gastroenterology, Hepatology and Liver Transplantation, Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany, Laue, Tobias; 2Pediatric Gastroenterology, Hepatology and Liver Transplantation, Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany, Ohlendorf, Johanna, Richter, Nicolas; 3Department of General, Visceral and Transplant Surgery, Hannover Medical School, 30625 Hannover, Germany, Ohlendorf, Johanna; 2Pediatric Gastroenterology, Hepatology and Liver Transplantation, Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany, Leiskau, Christoph; 1Pediatric Gastroenterology, Department of Pediatrics and Adolescent Medicine, University Medical Centre Göttingen, Georg August University Goettingen, 37075 Goettingen, Germany, Junge, Norman, Vondran, Florian W. R., Richter, Nicolas, Leiskau, Christoph, Laue, Tobias, Baumann, Ulrich   +17 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

The prognostic value of microvascular invasion in early-intermediate stage hepatocelluar carcinoma: a propensity score matching analysis

BMC Cancer, 2018
Background Microvascular invasion (MVI) is well established as a negative prognostic factor for hepatocelluar carcinoma (HCC). However, its prognostic value in different subgroups of Barcelona Clinical Liver Cancer (BCLC) stages remains to be elucidated.
Junyi Shen, Jun Wen, Chuan Li, Tianfu Wen, Lvnan Yan, Bo Li, Jiayin Yang, Changli Lu   +7 more
doaj   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Increased morbidity associated with secondary abdominal closure in pediatric liver transplantation

World Journal of Pediatric Surgery
Background The discrepancy in size between donor and recipient presents a complex challenge in pediatric liver transplantation (PLT), often necessitating secondary abdominal closure to prevent abdominal compartment syndrome.
Carolina Magalhães Costa, Eduardo A Fonseca, Renata Pugliese, Marcel R Benavides, Rodrigo Vincenzi, Nathália P T Rangel, Caio M Oliveira, Karina Roda, Debora P Fernandes, João Seda Neto   +9 more
doaj   +1 more source