Results 71 to 80 of about 1,150,856 (250)

A novel combined systemic inflammation-based score can predict survival of intermediate-to-advanced hepatocellular carcinoma patients undergoing transarterial chemoembolization

BMC Cancer, 2018
Background There is currently limited information regarding the prognostic ability of the dNLR-PNI (the combination of the derived neutrophil-to-lymphocyte ratio [dNLR] and prognostic nutritional index [PNI]) for hepatocellular carcinoma (HCC).
Chang Liu, Lei Li, Wu-sheng Lu, Hua Du, Lu-nan Yan, Tian-fu Wen, Wu-ran Wei, Li Jiang, Ming-qing Xu   +8 more
doaj   +1 more source

An mALBI-Child–Pugh-based nomogram for predicting post-hepatectomy liver failure grade B–C in patients with huge hepatocellular carcinoma: a multi-institutional study

World Journal of Surgical Oncology, 2022
Objective Post-hepatectomy liver failure (PHLF) is a severe complication in patients with hepatocellular carcinoma (HCC) who underwent hepatectomy.
Ming-Hao Xu, Bin Xu, Chen-Hao Zhou, Zhong Xue, Zhao-Shuo Chen, Wen-Xin Xu, Cheng Huang, Xiao-Dong Zhu, Jian Zhou, Jia Fan, Hui-Chuan Sun, Ying-Hao Shen   +11 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Survival of children after liver transplantation for hepatocellular carcinoma [PDF]

, 2018
Hepatocellular carcinoma (HCC) in childhood differs from adult HCC because it is often associated with inherited liver disease. It is, however, unclear whether liver transplantation (LT) for HCC in childhood with or without associated inherited disease ...
D'Antiga, L, Baumann, U, Mikolajczyk, R, Colledan, M, Ericzon, B-G, Chardot, C, Duvoux, C, Karam, V, Adam, R, Coker, A   +9 more
core   +2 more sources

Retained Foreign Body in Transplanted Liver

International Journal of Organ Transplantation Medicine, 2015
Liver transplantation is a technically complex and long surgical procedure. A large quantity of various materials such as catheters, sutures, needles and clips are frequently used during the procedure.
C Kayaalp, S K?rm?z?, R Kutlu, MA Yagci, B Isik, S Yilmaz   +5 more
doaj  

Toripalimab combined with lenvatinib and GEMOX is a promising regimen as first-line treatment for advanced intrahepatic cholangiocarcinoma: a single-center, single-arm, phase 2 study

Signal Transduction and Targeted Therapy, 2023
Advanced intrahepatic cholangiocarcinoma (ICC) has a dismal prognosis. Here, we report the efficacy and safety of combining toripalimab, lenvatinib, and gemcitabine plus oxaliplatin (GEMOX) as first-line therapy for advanced ICC.
Guo-Ming Shi, Xiao-Yong Huang, Dong Wu, Hui-Chuan Sun, Fei Liang, Yuan Ji, Yi Chen, Guo-Huan Yang, Jia-Cheng Lu, Xian-Long Meng, Xin-Ying Wang, Lei Sun, Ning-Ling Ge, Xiao-Wu Huang, Shuang-Jian Qiu, Xin-Rong Yang, Qiang Gao, Yi-Feng He, Yang Xu, Jian Sun, Zheng-Gang Ren, Jia Fan, Jian Zhou   +22 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Living Related Donor Liver Transplantation with Atrio- Caval Anastomosis of Inferior Vena Cava Graft Stored in Deep-Freeze for Budd-Chiari Syndrome

International Journal of Organ Transplantation Medicine, 2015
We have previously reported our experience in inferior vena cava resection and reconstruction techniques during liver transplantation for Budd-Chiari syndrome.
F Yaylak, V Ince, B Barut, B Unal, M Kilic, S Yilmaz   +5 more
doaj  

Liver transplantation for Wilson's disease: The burden of neurological and psychiatric disorders

, 2005
A retrospective data analysis on liver transplantation for Wilson's disease (WD) was performed among Italian Liver Transplant Centers. Thirty-seven cases were identified. The main indication for liver transplantation was chronic advanced liver disease in
Andriulli, A, Grazi G. L., S.t.u.r.n.i.o.l.o. GC, Aresu G., Castagneto M., FASSATI L. R, Slim A. O. , Strazzabosco M, Mirante, VG, Trevisan, CP, MIRANTE V. G, FAGIUOLI S., Rapaccini G. L., Rondinara, GF, CILLO, UMBERTO, Filla A., Del Gaudio, M, Salizzoni, M, MEDICI, VALENTINA, Valente U. , Zanus G., Burra P., Forti, D, Medici, V, Angelico, M, TREVISAN, CARLO PIETRO, ANGELICO, MARIO, Melada E., Sturniolo. GC, Caccamo L., Tisone, G, Pompili, Maurizio, Fagiuoli, S, Marzano A., Valente U., Zanus G., TISONE, GIUSEPPE, DEL GAUDIO M, Cillo, U, Nardo B., D'Amico D. F., POMPILI M, Aresu G., Burra P., Caccamo L., Castagneto M., D'Amico D.F., Dardano G., Filla A., Gasbarrini A., Gasbarrini G., Gianni S., Grazi G.L., Martines D., Marzano A., Melada E., Nardo B., Pevere S., Rapaccini G.L., Rizzetto M., Rondinara, GF, Gasbarrini G., Pevere S., Gasbarrini A., Martines D., Rizzetto M., FORTI D, Slim A.O., Strazzabosco M, Gianni S., Dardano G., STURNIOLO, GIACOMO, Fassati, LR, Pompili, M   +51 more
core   +1 more source