Development of Non-Invasive Continuous Glucose Prediction Models Using Multi-Modal Wearable Sensors in Free-Living Conditions. [PDF]
Karunarathna TS, Liang Z.
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Quantification of Differences in Sleep Measurement by a Wrist-Worn Consumer Wearable Compared to Research-Grade Accelerometry and Sleep Diaries of Female Adults in Free-Living Conditions. [PDF]
Hu CR +14 more
europepmc +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Madagascar rural observatory surveys, a longitudinal dataset on household living conditions 1995-2015. [PDF]
Andrianjafindrainibe VS +16 more
europepmc +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Impact of the improvement of living conditions on tuberculosis mortality in Brazil: an ecological study. [PDF]
Natividade M +11 more
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Asynchronous movement of sarcomeres in myocardium under living conditions: role of titin. [PDF]
Kobirumaki-Shimozawa F +4 more
europepmc +1 more source

