Results 111 to 120 of about 380,564 (310)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Organ Quality as a Complicating Factor in Proposed Systems of Inducements for Organ Donation [PDF]

, 2014
En typisk funktion på startsidan till många webbportaler är den webbdel som presenterar exempelvis desenaste blogginläggen, nyheterna eller händelserna som har lagts till på webbplatsen. Dessa funktioner ärkända som aggreggeringswebbdelar.
Volk, Michael L.
core   +2 more sources

Liver retransplants using living donors: An approach for management. [PDF]

Liver Res, 2023
Al Harakeh H, Hughes C, Tevar A, Gunabushanam V, Ashwat E, Liu H, Humar A.   +6 more
europepmc   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

An uneasy reality: Donor support for IDPs in Ukraine Łukasz Wenerski, Andriy Korniychuk, Oleksandr Kliuzhev (cooperation) [PDF]

, 2019
According to international organizations, since the annexation of Crimea and the beginning of the war in Donbas, internal migrations might have affected from two to three million people. From Crimea and Donbas alone, 1.5 million Ukrainian citizens had to
Kliuzhev, Oleksandr, Korniychuk, Andriy, Wenerski , Lukasz   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Increasing the Rate of Living Donor Kidney Transplantation in Ontario: Donor- and Recipient-Identified Barriers and Solutions

Canadian Journal of Kidney Health and Disease, 2017
Purpose of Review: To hear from living kidney donors and recipients about what they perceive are the barriers to living donor kidney transplantation, and how patients can develop and lead innovative solutions to increase the rate and enhance the ...
Leah E. Getchell, Susan Q. McKenzie, Jessica M. Sontrop, Jade S. Hayward, Megan K. McCallum, Amit X. Garg   +5 more
doaj   +1 more source

Open and laparoscopic living donor nephrectomy in Switzerland: a retrospective assessment of clinical outcomes and the motivation to donate [PDF]

, 2017
Background. Laparoscopic living kidney nephrectomy is thought to be associated with reduced morbidity, when compared to open nephrectomy. The purpose of this study was to explore the impact of these techniques on donors' clinical outcomes, satisfaction ...
Cao, Claude, Clavien, Pierre-Alain, Dahm, Felix, Laube, Guido F., Müller, Benjamin, Neuhaus, Thomas J., Pradel, Françoise G., Thiel, Gilbert T., Weber, Markus, Wüthrich, Rudolf P.   +9 more
core  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Relationship of Social Deprivation Among Living Kidney Donor–Recipient Pairs

Transplantation Direct
Background. Living kidney transplant is the most effective renal replacement therapy for patients with end-stage kidney disease. Community-level factors contribute to pervasive socioeconomic and racial disparities in access to living donor kidney ...
Yara Bilen, MD, Jesse D. Schold, PhD, Susana Arrigain, MA, R. Blake Buchalter, PhD, Anne M. Huml, MD   +4 more
doaj   +1 more source