Results 101 to 110 of about 8,459,231 (297)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Transdisciplinary Living Lab Model (TDLL)

, 2019
A Transdisciplinary Living Lab Model (TDLL) was developed in collaboration with two Australian Universities: the University of Technology Sydney and Western Sydney University. This TDLL model takes a transdisciplinary approach to learning while utilizing
Fam, Dena, Ross, Katie, Crosby, Alexandra, Dena Fam, Mellick Lopes, Abby (R11243), Abby Mellick Lopes, Alexandra Crosby, Katie Ross   +7 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

De Omarming: A dementia friendly living environment

, 2020
A living environment designed for elderly people and elderly people with dementia. If the residents, the elderly people, gets dementia they will be able to continue their life in the same, trusted living environment, without moving to other living ...
Ezink, Jeroen (author)
core  

Exploratory Action Research on Renovating Room Plans for Vacant Apartments Based on the Living Conditions of Young Working Households and Real Estate Data

Japan Architectural Review
This study examines practical layout renovations based on actual living and unit specifications. In Osaka City, significant correlations were found between the number of cohabitants and the apartment layout (R2 = 0.50), floor area (0.32), and rent (0.26)
Daisuke Matsushita, Tamao Naoe, Mei Nakagawa, Ayame Sato, Shushi Doi   +4 more
doaj   +1 more source

Towards Inclusive and Resilient Living Environments for Older Adults: A Methodological Framework for Assessment of Social Sustainability in Nursing Homes

Buildings
The quality of living environments for older adults represents a critical component of social sustainability in an ageing society. Among various housing options, nursing homes are the most institutionalised form of elderly care and demand special ...
Vanja Skalicky Klemenčič, Vesna Žegarac Leskovar   +1 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Associations of neighborhood infrastructure with cardiovascular diseases and their risk factors: results of the ESSE-RF-3 epidemiological study

Кардиоваскулярная терапия и профилактика
Aim. To analyze the association of neighborhood infrastructure with cardiovascular diseases (CVDs) and their risk factors (RFs) in a representative all-Russian adult population sample.Material and methods.
S. A. Maksimov, M. B. Kotova, S. A. Shalnova, Yu. A. Balanova, A. E. Imaeva, V. А. Kutsenko, S. E. Evstifeeva, A. V. Kapustina, G. A. Muromtseva, N. S. Karamnova, O. B. Shvabskaya, T. V. Repkina, T. O. Gonoshilova, A. V. Kudryavtsev, N. I. Belova, L. L. Shagrov, M. A. Samotrueva, A. L. Yasenyavskaya, O. A. Bashkina, S. V. Glukhovskaya, I. A. Levina, E. A. Shirshova, E. B. Dorzhieva, E. Z. Urbanova, N. Yu. Borovkova, V. K. Kurashin, A. S. Tokareva, Yu. I. Ragino, G. I. Simonova, A. D. Khudyakova, V. N. Nikulin, O. R. Aslyamov, G. V. Khokhlova, A. V. Solovyova, A. A. Rodionov, O. V. Kryachkova, Yu. Yu. Shamurova, E. V. Mikhailov, Yu. O. Tarabrina, M. G. Ataev, M. O. Radzhabov, Z. M. Gasanova, M. A. Umetov, I. A. Khakuasheva, L. V. Elgarova, E. I. Yamashkina, L. A. Balykova, A. A. Usanova, A. M. Nikitina, N. V. Savvina, Yu. E. Spiridonova, E. A. Naumova, V. S. Yudin, A. A. Keskinov, S. M. Yudin, A. V. Kontsevaya, O. M. Drapkina   +56 more
doaj   +1 more source

Design and the living environment

, 1974
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source