Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Environment, urban living and One Health: the lens of Land Systems
Environment, urban living and One Health Anthropogenic stressors on our environment, such as biodiversity loss, climate change, pollution, and land use change (deforestation, urbanization,…) also threaten the health of humans and animals.
One Health – Research and Innovation at the crossroads of environment and health. +1 more
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The influence mechanisms of living environment on the physical and mental health of Chinese older adults: a cross-sectional exploration based on CLASS 2023. [PDF]
Sci RepWu Y.
europepmc +1 more source
A Machine Learning Pipeline for Gait Analysis in a Semi Free-Living Environment. [PDF]
Sensors (Basel), 2023 Jung S +6 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Perceived Accessibility of Living Environment and Services Questionnaire: Validity and Reliability. [PDF]
OTJR (Thorofare N J)Segev-Jacubovski O.
europepmc +1 more source
Assessment of Doubly Disadvantaged Neighborhoods by Healthy Living Environment Exposure. [PDF]
Appl Spat Anal Policy, 2023 Liu D, Kwan MP, Kan Z.
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Clarifying the meaning of a positive living environment in nursing homes: A scoping review protocol. [PDF]
PLoS OneJanssens L +4 more
europepmc +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source