Results 141 to 150 of about 3,377,831 (304)
Museum Theatre in Greece: Perspectives in Site Interpretation
EXARC Journal, 2015 The paper summarizes preliminary findings of a research project on the use of museum theatre in Greek open-air sites, as a part of a PhD thesis. The research focuses on the exploration of the development, use and function of museum theatre in Greek open ...
Foteini Venieri, Niki Nikonanou
doaj
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
The Value of Experience: Lessons from a Study of Reenactment
EXARC Journal, 2016 It is no secret that in many ways experimental archaeology overlaps with what has come to be called experiential archaeology, an interpretive and humanistic approach to the past.
Samantha Hartford
doaj
Lee and His Lieutenants: An Interview with Keith Bohannon
, 2018 Over the course of this year, we’ll be interviewing some of the speakers from the upcoming 2018 CWI conference about their talks. Today we are speaking with Dr.
Luskey, Ashley Whitehead
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The VIA SCIPIONIS Project Outdoor Travelling Experimental Archaeology and Re-enactment
EXARC Journal, 2016 In August 2015 the first rendition of an experimental archaeology project was held, for the first time in Spain. The objective was to study the problems faced by the Roman Republican legions from the second Punic War during their marches.
José Miguel Gallego Cañamero +3 more
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
EXARC Journal, 2018 Archaeological time travel, or experiencing the past through re-enactment, virtual reality, popular culture or other means, is presented from multiple perspectives in The Archaeology of Time Travel.
Silje Evjenth Bentsen
doaj
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The Forgotten Movement – A (Re)construction of Prehistoric Dances
EXARC Journal, 2018 Dancing has always been and still is an integral part of the lives of individuals and communities around the world, and it forms part of the cultural identity of all traditional societies.
Ivana Turčin
doaj