Results 91 to 100 of about 912,341 (301)
Co-creating a cancer screening dashboard with screening invitees and experts
GMS Medizinische Informatik, Biometrie und EpidemiologiePopulation-based screenings for cervical, breast, and colorectal cancer in the Netherlands enable early detection, yet participation has declined. Some invitees, particularly vulnerable groups, struggle with informed decision-making.
Oldhoff-Nuijsink, Corine +5 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Methodological Framework for implementing and evaluating Living Labs [PDF]
, 2008 A Living Lab constitutes a research approach for innovation that challenges the whole research and innovation process in real-life conditions by human, social, cultural, organizational and institutional aspects having an impact on sustainable service ...
García Guzmán, Javier
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Living Lab in Computer Information Technology [PDF]
, 2011 poster abstractResearch Subject is the Living Lab in CIT, an experiential learning environment where students gain real IT experience.The Living Lab allows students to apply networking, security, database, website, and application development concepts ...
Justice, Connie
core
Integrative concept of homeostasis: translating physiology into medicine [PDF]
, 2011 To truly understand living systems they must be viewed as a whole. In order to achieve this and to come to some law to which living systems obey, data obtained on cells, tissues and organs should be integrated.
Ivan Spasojevic, Ivan Spasojevic
core +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Suomen Maataloustieteellisen Seuran Tiedote, 2010 Käytettävyys on tuotteen ominaisuus, joka määrittelee, kuinka hyvin tuote vastaa tavoiteltua käyttötarkoitustaan ja kuinka hyvin käyttäjä pystyy hyödyntämään tuotteen toimintoja. Hyvä käytettävyys havaitaan mm. tuotteen käytön helppoutena, nopeutena ja miellyttävyytenä.
Esala, Jussi, Kankaanpää, Sanna
openaire +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source