Results 171 to 180 of about 1,716,496 (303)

The impact of enhanced recovery after surgery care on postoperative limb function and prognosis in patients with cranio-cerebral trauma

Asian Journal of Surgery
Fang Cheng, Zhengui Li, Wanqian Su, Jingjing Song   +3 more
doaj   +1 more source

Testing for human immunodeficiency virus. [PDF]

Aust Prescr
Owen L, Woolley I.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Validity and Reliability of Using a Belt-Worn Accelerometer on the Lower Back to Monitor Physical Activity. [PDF]

Sensors (Basel)
Williamson SL, Luo J, Albery IP.
europepmc   +1 more source

Houses of Experiment:Modern housing and the will to laboratorization [PDF]

, 2013
Jacobs, Jane, Strebel, Ignaz
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Neighborhood walkability and sedentary behaviors among US adults. [PDF]

Environ Epidemiol
Deng Y, Moniruzzaman M, Rogers B, Jayasekera J, Hu L, Nakaya T, Ben-Joseph E, Berrigan D, Matthews CE, Tamura K.   +9 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Children and adolescents living with human immunodeficiency virus/acquired immunodeficiency syndrome in a tertiary hospital in southern Brazil. [PDF]

Rev Paul Pediatr
Silveira SS, Bolinsenha MPDS, Rossoni YO, Silveira SS, Lugarini G, Tahan TT, Hirose TE, Rodrigues CO, Caprilhone LW, Rossoni AMO, Gabardo BMA.   +10 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source