Results 141 to 150 of about 2,046,162 (340)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Control of disinfection by-products in drinking water systems

, 2007
The occurrence of disinfection by-products (DBPs) in drinking water has been an issue of major concern during several decades. The formation of many DBPs species during water disinfection has been documented, while new by-products are still being ...
Selçuk, Hüseyin, Rizzo, L., Nikolaou, A.   +2 more
core  

Systems Biology and Microgravity Effects on Living Organisms

, 2014
Gravity has constantly influenced biological phenomena throughout all the Earth’s history. The gravitational field has probably played a major role in shaping evolution when life moved from water to land, even if, for a while, it has been generally ...
M, Bizzarri
core   +1 more source

Research on resilience regulation of water resource systems in the Yellow River basin under during extreme drought years

Shui kexue jinzhan
Under changing environmental conditions，water-scarce basins are facing increasingly severe conflicts between water supply and demand. Therefore，there is an urgent need to innovate and develop methods and technologies to regulate water resource resilience
Yu WANG, Xiaokang ZHENG, Hong LYU, Shaoming PENG, Xiangnan ZHOU, Wenxiu SHANG, Di ZHANG   +6 more
doaj   +1 more source

Water in Living Systems [PDF]

Nature, 1966
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

On-site wastewater reuse technology options in Australia

, 1999
Domestic wastewater reuse is currently not permitted anywhere in Australia but is widely supported by the community, promoted by researchers, and improvised by up to 20% of householders. Its widespread implementation will make an enormous contribution to
Dallas, S., Mathew, K., Anda, M., Ho, G.
core  

From Prototypes to Living Labs: Advancing Sustainability Education in Rwanda and Côte d’Ivoire

Journal of Sustainable Development of Energy, Water and Environment Systems
This paper evaluates the outcomes of two projects, “Industry-Integrated Dual Engineering Studies in a North-South Collaboration" in Côte d’Ivoire and "Growing Rwanda Energy Awareness Through Higher Education" in Rwanda.
Lisa Schmitt, Charlotte Newiadomsky, Arne Graßmann   +2 more
doaj   +1 more source

A Systematic Literature Review on Flow Data-Based Techniques for Automated Leak Management in Water Distribution Systems

Smart Cities
Smart cities integrate advanced technologies, data-driven decision-making, and interconnected infrastructure to enhance urban living and resource efficiency.
Gopika Rajan, Songnian Li
doaj   +1 more source

Electric and magnetic phenomena in water and living systems [PDF]

We are called organisms because our cells are organized into a cooperative\ud assemblage of interacting elements. Human beings are more\ud than simply bags of interacting chemicals walking around enclosed\ud within 1.8 square metres of skin. It has long been known that\ud biological organisms, including ourselves, use chemical communication\ud systems.
openaire