Results 141 to 150 of about 284,893 (258)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Polymer chemistry at the living-material interface. [PDF]

Chem Sci
Kawada M, Sim S.
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Fragility of Immunisation and Water Systems in Gaza: Infectious Disease Risks in a Conflict-Affected Setting. [PDF]

Infez Med
Scotto A, Fazio V, Scotto G.
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Nitrogen Fixation Associated with <i>Microcystis</i> Colonies Promotes Harmful Cyanobacterial Blooms across North American Lakes. [PDF]

Environ Sci Technol
Gobler CJ, Famularo-Pecora AME, Kramer BJ, Jankowiak JG, Goleski JA, Hem R, Turk-Kubo KA, Zehr JP.   +7 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Entropy Bathtub for Living Systems: A Markovian Perspective. [PDF]

Entropy (Basel)
Fornalski KW.
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Ecosystem technology (ecotech): Harnessing natural processes to address global challenges. [PDF]

Sci Adv
Silliman BR, Hensel MJS, Temmink RJM, Paxton AB, Wieczynski DJ, Gibert JP, Johnston DW, Noonan D, Ferris WN, Hay ME, Paalman T, Cutshaw C, Borsuk M, Angelini C, Dalton LE, van de Koppel J, van Belzen J, Strong B, Bertness MD, Angelini TE, Gutierrez AW, Thomsen MS, Kaynor T, Olander L, Cassar N, Stoorvogel MM, Bouma TJ, Wear S, van der Heide T, Daleo P, Parker S, Aithal A, Gittman RK, Silliman P, Wade E, Rungta D, Qiu T, He L, Cerino DS, He Q, von Windheim J, Nordone SK.   +41 more
europepmc   +1 more source