Results 191 to 200 of about 5,731,886 (249)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Valued Living intervention to increase advance care planning and well-being in depressed and anxious adults with advanced cancer: Randomized trial in community oncology clinics. [PDF]

Cancer
Arch JJ, Mitchell JL, Schmiege SJ, Levin ME, Nealis MS, Genung SR, Fink RM, Andorsky DJ, Kutner JS.   +8 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Communities of Practice and Living Labs: A Scoping Review of Principles and Methodologies for Involvement of Lived Experience Experts in Health and Healthcare Research. [PDF]

Health Expect
Watson E, Afrin S, Long KM, Giebel C, Moran C, Ayton D.   +5 more
europepmc   +1 more source

National and State Societal Costs of Schizophrenia in the US in 2024.

JAMA Psychiatry
Krasa HB, Baumgardner JR, Brewer IP, Chou JW, Flottemesch T, Markowitz JT, Williams C, Nagendra A.   +7 more
europepmc   +1 more source

Views on an antipsychotic regimen administered once every 2 months: a qualitative interview study of people living with bipolar I disorder, caregivers, and prescribers in the USA and Canada. [PDF]

Int J Bipolar Disord
Tohen M, Yildirim M, Loomer S, Micheelsen A, Harrsen K, Beckham C, Nag S, Bates D, Guillaume X, Such P.   +9 more
europepmc   +1 more source

Editorial: Preventing obesity-related degenerative diseases through lifestyle changes. [PDF]

Front Sports Act Living
Lu S, Shen Y, Hu G, Jian D, Wang C.
europepmc   +1 more source

Intelligent living environments and older adults' health outcomes: roles of social support and self-efficacy. [PDF]

BMC Public Health
Peng Y, Liu Z.
europepmc   +1 more source

Analysis of influencing factors and prediction of falls among rural older adults in China based on a nomogram model. [PDF]

Front Public Health
Wu Y, Cao S, Wan P, Liu Y, Zhao Y, Chen Y, Li Y, Ding H.   +7 more
europepmc   +1 more source