Results 81 to 90 of about 1,879 (215)

Physical and Chemical Characterization of Soil in Urban Solid Waste Disposal Area

Land Degradation &Development, EarlyView.
ABSTRACT Waste generation and subsequent disposal in adequate sites still have limitations in some Brazilian municipalities. Therefore, environmental monitoring of these areas is extremely important, as it helps to preserve the environment. The purpose of this study is to analyze the chemical and physical parameters of soil in a landfill area. For this,
Mayara Aline Bones, Willian Fernando de Borba, Pedro Daniel da Cunha Kemerich, Cristiane Carine dos Santos, Jaqueline Ineu Golombieski, Lucindo Somavilla, Marcela de Melo Torchelsen, Claiton Nardini, Luma Schervenski Tejada, Mateus Guimarães da Silva   +9 more
wiley   +1 more source

A Case Series on Streptococcus agalactiae Infection in Llamas and Alpacas in a Semi-Intensive Breeding System in Southern Brazil

Veterinary and Animal Science
The South American Camelids (CSA), including llamas (Lama glama) and alpacas (Vicugna pacos), are primarily concentrated in the Andean countries of Argentina, Bolivia, Chile, and Peru, where they represent an important source of income for the local ...
Vitor Eduardo Mamgue, Letícia Trevisan Gressler, Andriel Gustavo Felichak, Paulo Henrique Braz   +3 more
doaj   +1 more source

Challenges of Pain in Parkinson's Disease: Results from the OCEAN Study

Movement Disorders, EarlyView.
Abstract Background Pain is a common non‐motor symptom in Parkinson’s disease (PD) and is often associated to fluctuations. Objective The OpiCapone Effect on motor fluctuations and pAiN (OCEAN) study evaluated the effect of opicapone on fluctuation‐related pain when added to levodopa therapy in PD patients.
Kallol Ray Chaudhuri, Joaquim J. Ferreira, Angelo Antonini, Olivier Rascol, Monica M. Kurtis, Alexander Storch, José‐Francisco Rocha, Raquel Costa, Diogo Magalhães, Guillermo Castilla‐Fernández, Helena C. Brigas, Joerg Holenz, Per Odin, on behalf of the OCEAN study group   +13 more
wiley   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1.

PLoS Pathogens, 2014
To date, no immunization of humans or animals has elicited broadly neutralizing sera able to prevent HIV-1 transmission; however, elicitation of broad and potent heavy chain only antibodies (HCAb) has previously been reported in llamas.
Laura E McCoy, Lucy Rutten, Dan Frampton, Ian Anderson, Luke Granger, Rachael Bashford-Rogers, Gillian Dekkers, Nika M Strokappe, Michael S Seaman, Willie Koh, Vanina Grippo, Alexander Kliche, Theo Verrips, Paul Kellam, Ariberto Fassati, Robin A Weiss   +15 more
doaj   +1 more source

AI/ML Enabled High‐Throughput Design and Synthesis for Energetic Molecules

Materials Genome Engineering Advances, EarlyView.
Novel design methods for a special kind of functional molecules — the energetic molecules—are summarized. Both classic Machine Learning (ML) and Artificial Intelligence (AI) generative models are utilized for the high‐throughput design of these energetic molecules, and a sort of high‐energy low‐sensitivity molecules are obtained.
Wen Qian
wiley   +1 more source

Lethal Bluetongue Virus Serotype 1 Infection in Llamas

Emerging Infectious Diseases, 2009
Gilles Meyer, Caroline Lacroux, Sébastien Léger, Sokunthea Top, Katel Goyeau, Martine Deplanche, Mylène Lemaire   +6 more
doaj   +1 more source

Muscle‐Specific Kinase Signaling and Its Therapeutic Potential

Muscle &Nerve, EarlyView.
ABSTRACT The function of the neuromuscular junction (NMJ) is compromised in many neuromuscular diseases (NMDs) such as autoimmune or congenital myasthenia gravis (MG), amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and muscular dystrophies.
Stine Marie Jensen, Dana L. E. Vergoossen, Maartje G. Huijbers   +2 more
wiley   +1 more source

The impact of zoo education programmes on connection to nature considering programme type, participants' demographics and their initial connection

People and Nature, EarlyView.
Abstract Participants in environmental education programmes can have different preexisting attitudes and experiences that could influence the educational outcomes. The present study focuses on zoo education and its goal of connecting people to nature.
Viktoria Feucht, Paul Wilhelm Dierkes, Martin Bratteler, Anna Bresser, Sandra Buchberger, Jule Hadler, Andreas Haeser‐Kalthoff, Elia Heule, Axel Kästner, Constanze Mager, João Neves, Kathrin Rapp Schürmann, Kathrin Monika Röper, Rebecca D. Schulte‐Iserlohe, Lisa Schwarz, Tanja Spengler, Marcel Stawinoga, Ina Steinert, Franziska Waked, Stephan Worm, Matthias Winfried Kleespies   +20 more
wiley   +1 more source

Large language models unlock large text corpora in the search for data on medicinal plants and fungi

PLANTS, PEOPLE, PLANET, EarlyView.
Millions of people worldwide depend on plants and fungi for their healthcare needs, yet our understanding of which species are used medicinally—and how—remains fragmented and incomplete. As part of Kew's Plants for Health service, we developed a pipeline to mine large text corpora for information on natural products, initially focusing on the medicinal
Adam Richard‐Bollans, Francesco Civita, Tiziana A. Cossu, Ifra Saifi, Kristina Patmore, Caroline Wilkinson, Bob Allkin   +6 more
wiley   +1 more source