Results 41 to 50 of about 1,395,480 (391)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Estudo dos valores do limite de liquidez obtidos pelos métodos de Casagrande e Cone para diferentes argilas

open access: yesGeotecnia, 2017
Neste estudo comparam-se os valores do limite de liquidez, LL, obtidos pelo método do Cone de Penetração, LLp, com os valores de LL obtidos pelos métodos de Casagrande, LLc, medidos, por diferentes operadores, em amostras de solos argilosos de alta e ...
Kátia Vanessa Bicalho   +3 more
doaj   +1 more source

City Wide Adhan as heard from the top of Cairo Tower on 01-25-2010 at 3:06pm: Asr Adhan [PDF]

open access: yes, 2010
Five times a day in the 83 square mile city of Cairo, over 30,000 muezzins call out the adhan, or call to prayer, calling believers to come and to pray.
Kipervaser, Anna, LLC, On Look Films
core  

Three-Phase Series Resonant DC-DC Boost Converter With Double LLC Resonant Tanks and Variable Frequency Control

open access: yesIEEE Access, 2020
This paper proposes a three-phase inverter combined with two LLC resonant tanks series resonant DC-DC boost converter with variable frequency control. The three-phase inverter side of the proposed circuit is connected to identical two-level LLC tanks to ...
Mohamed Salem   +6 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Beach Profile, Water Level, and Wave Runup Measurements Using a Standalone Line-Scanning, Low-Cost (LLC) LiDAR System

open access: yesRemote Sensing, 2022
A prototype rapidly deployable, Line-scanning, Low-Cost (LLC) LiDAR system (USD 400 per unit; 2020) was developed to measure coastal hydro-morphodynamic processes. A pilot field study was conducted at the U.S.
Christopher S. O’Connor   +1 more
doaj   +1 more source

City Wide Adhan as heard from Shera Falaky on 01-15-2010 at 5:21am: Fajr Adhan [PDF]

open access: yes, 2010
Five times a day in the 83 square mile city of Cairo, over 30,000 muezzins call out the adhan, or call to prayer, calling believers to come and to pray.
Kipervaser, Anna, LLC, On Look Films
core  

Action Classification with Locality-constrained Linear Coding [PDF]

open access: yes, 2014
We propose an action classification algorithm which uses Locality-constrained Linear Coding (LLC) to capture discriminative information of human body variations in each spatiotemporal subsequence of a video sequence. Our proposed method divides the input
Huynh, Du   +3 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The rule of five should not impede anti-parasitic drug development

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2017
The “rule of 5” has become a mainstay of decision-making in the pharmaceutical industry as well as in nonindustrial (academic and institutional) drug development.
James H. McKerrow   +1 more
doaj   +1 more source

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