Results 81 to 90 of about 2,089,832 (287)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Evaluation of the Performance of Vortex Generators on the DU 91-W2-250 Profile using Stereoscopic PIV [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2009
Stereoscopic PIV measurements investigating the effect of Vortex Generators on the lift force near stall and on glide ratio at best aerodynamic performance have been carried out in the LM Glasfiber wind tunnel on a DU 91-W2-250 profile.
Clara Marika Velte   +3 more
doaj  

C-system of a module over a monad on sets [PDF]

open access: yes, 2014
This is the second paper in a series that aims to provide mathematical descriptions of objects and constructions related to the first few steps of the semantical theory of dependent type systems. We construct for any pair $(R,LM)$, where $R$ is a monad
Voevodsky, Vladimir
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Land Re-Use, Complexity And Actor-Networks: A Framework For Research [PDF]

open access: yes
This paper will present a conceptual framework for the examination of land redevelopment based on a complex systems/networks approach. As Alvin Toffler insightfully noted, modern scientific enquiry has become exceptionally good at splitting problems into
Joe Doak, Nikos Karadimitriou
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Identification of semen traces at a crime scene through Raman spectroscopy and machine learning

open access: yesScientific Reports
Biological fluid stains can be instrumental in solving crimes. Identification of semen can help reconstruct events in sexual assault cases and identify suspects via DNA profiling.
Alexey V. Borisov   +5 more
doaj   +1 more source

Expert judgement in the Processes of Commercial Property Market Forecasting [PDF]

open access: yes
In this paper we investigate the role of judgement in the formation of forecasts in commercial real estate markets. Based on interview surveys with the majority of forecast producers, we find that real estate forecasters are using a range of inputs and ...
Patrick McAllister, Paul Gallimore
core  

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

Effect of Dry Buffered Vinegar on Listeria Monocytogenes Growth during Shelf Life on Ready-to-Eat Beaten Beans Dip

open access: yesScientific Papers Animal Science and Biotechnologies
The beaten beans dip represents one of the most popular foods in Romania; it is frequently consumed, and it is on the manufacturing list of many food producers as ready to eat (RTE) meal. This category of RTE, generally, recognizes aw and pH values which
Georgeta Ștefan   +2 more
doaj  

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