Results 191 to 200 of about 13,097 (262)

Reduction in hippocampal cholinergic neurostimulating peptide enhances memory impairment in AppNL‐G‐F KI mice

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Whether cholinergic activity in the septohippocampal network affects cognitive dysfunction via hippocampal cholinergic neurostimulating peptide (HCNP) in Alzheimer's pathogenesis remains unclear. METHODS An Alzheimer's pathogenesis by mutation in amyloid‐beta precursor protein gene (AppNL‐G‐F) knock‐in (KI) and HCNP precursor ...
Yo Tsuda   +10 more
wiley   +1 more source

The include network: Advancing cross‐linguistic equity in brain health research

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Speech and language measures are increasingly recognized as sensitive, scalable, non‐invasive markers of diverse brain disorders. Yet, current research is overwhelmingly English‐centric, neglecting the world's vast linguistic diversity and undermining these markers’ global applicability.
Adolfo M. García   +13 more
wiley   +1 more source

Five‐year change in brain metabolism across the spectrum of cognitive impairment in older adults: a quantitative MRI study

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION It is desirable to measure brain metabolism without needing ionizing radiation and elucidate its time trajectory. This study employed a positron emission tomography ‐validated, non‐invasive magnetic resonance imaging (MRI) technique to characterize longitudinal changes in cerebral metabolic rate of oxygen (CMRO2) in both ...
Jiani Wu   +14 more
wiley   +1 more source

Stable neuronal representations underlie cognitive resilience to Alzheimer's disease pathology

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION While Alzheimer's disease (AD) typically elicits progressive cognitive decline, some individuals with significant AD pathology maintain cognition. Understanding the neuronal underpinnings of such cognitive resilience would propel the development of interventions for delaying dementia.
Keying Chen   +9 more
wiley   +1 more source

Estimating and learning personality traits of and from women with borderline personality disorder. [PDF]

open access: yesBorderline Personal Disord Emot Dysregul
Doppelhofer LM   +5 more
europepmc   +1 more source

Brain Activity During the Gradual‐Onset Continuous Performance Task in Adolescents: An Exploratory fMRI Study

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
This exploratory fMRI study investigated neural mechanisms of sustained attention and inhibition in adolescents using two modalities of the gradCPT tasks. Brain activation during response inhibition showed modality‐specific patterns: face modality engaged left fronto‐cingulo‐cerebellar regions while scene modality activated bilateral fronto‐temporo ...
Jade Awada   +6 more
wiley   +1 more source

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