Results 151 to 160 of about 14,545 (178)
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Characterization of Adiposity and Metabolism in Lmna-Deficient Mice
Biochemical and Biophysical Research Communications, 2002Dunnigan's Familial Partial Lipodystrophy (FPLD) is an autosomal dominant disease characterized by regional fat loss and insulin resistance. FPLD is caused by mutations in the LMNA gene, which encodes intermediate filaments of the nuclear lamina. Different LMNA mutations cause Emery-Dreifuss muscular dystrophy and/or a dilated cardiomyopathy. It is not
Dedra A, Cutler +4 more
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LMNA mutations in progeroid syndromes.
Novartis Foundation symposium, 2005Segmental progeroid syndromes are disorders in which affected individuals. present various features that suggest accelerated ageing. The two best-known examples are Hutchinson-Gilford progeria syndrome (HGPS, 'Progeria of childhood') and Werner syndrome (WS, 'Progeria of the adult'). A novel, recurrent de novo mutation in the LMNA gene, responsible for
Shurong, Huang +2 more
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Circulation
Introduction/Background: LMNA (encoding gene lamin A/C) cardiomyopathy is associated with high morbidity and mortality. LMNA loss-of-function variants frequently lead to dilated cardiomyopathy with high arrhythmic burden, necessitating transplantation or resulting in heart failure.
Maria Viskadourou +10 more
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Introduction/Background: LMNA (encoding gene lamin A/C) cardiomyopathy is associated with high morbidity and mortality. LMNA loss-of-function variants frequently lead to dilated cardiomyopathy with high arrhythmic burden, necessitating transplantation or resulting in heart failure.
Maria Viskadourou +10 more
openaire +1 more source
Hippocampal LMNA Gene Expression is Increased in Late-Stage Alzheimer’s Disease
International Journal of Molecular Sciences, 2019Javier Sanchez-Ruiz De Gordoa +2 more
exaly