Results 141 to 150 of about 285,592 (275)

Polymorphism in lncRNA AC008392.1 and its interaction with smoking on the risk of lung cancer in a Chinese population

, 2018
Xiaoting Lv,1,2 Zhigang Cui,3 Hang Li,1,2 Juan Li,1,2 Zitai Yang,1,2 Yanhong Bi,1,2 Min Gao,1,2 Baosen Zhou,1,2 Zhihua Yin1,2 1Department of Epidemiology, School of Public Health, China Medical University, Shenyang, 110122, People’s Republic of ...
Li H, Yang Z, Li J, Gao M, Lv X, Cui Z, Zhou B, Bi Y, Yin Z   +8 more
core  

Omics Insights Into the Effects of Highbush Blueberry and Cranberry Crop Agroecosystems on Honey Bee Health and Physiology

PROTEOMICS, EarlyView.
ABSTRACT Honey bees (Apis mellifera) are vital pollinators in fruit‐producing agroecosystems like highbush blueberry (HBB) and cranberry (CRA). However, their health is threatened by multiple interacting stressors, including pesticides, pathogens, and nutritional changes.
Huan Zhong, Yuming Shi, Aleksandra Kozlova, Renata Moravcova, Jason C. Rogalski, Aidan Jamieson, Lance Lansing, Kyung‐Mee Moon, Xiaojing Yuan, Amanda S. Gregoris, Heather Higo, Julia Common, Ida M. Conflitti, Mateus Pepinelli, Lan Tran, Morgan Cunningham, Hosna Jabbari, Syed Abbas Bukhari, Sarah K. French, Rodrigo Ortega Polo, Shelley E. Hoover, Stephen F. Pernal, Pierre Giovenazzo, M. Marta Guarna, Amro Zayed, Leonard J. Foster   +25 more
wiley   +1 more source

Identifying lncRNA–Protein Interactions in Hematopoietic Progenitor Cells by Hybridization Capture and Mass Spectrometry

Journal of Proteome Research
Long noncoding RNAs (lncRNAs) exert regulatory functions in a wide spectrum of biological contexts, and certain regulatory functions involve the formation of RNA-protein complexes. Discovering the structure and function of these complexes may unveil important functional insights.
Yuling Dai, Jeong-Ah Kim, Isabella T. Whitworth, Mark Scalf, Mabel M. Jung, Brian L. Frey, Emery H. Bresnick, Lloyd M. Smith   +7 more
openaire   +2 more sources

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Molecular and genomic advances in breast cancer: A comprehensive review of predictive and therapeutic innovations

Precision Medical Sciences, EarlyView.
Breast cancer subtypes, estrogen receptor‐positive (ER+), HER2‐enriched, and TNBC, are defined by genomic and epigenetic signatures. Multi‐omics profiling, immunotherapy, liquid biopsy, and AI‐driven radiogenomics enable precision medicine. Tools like Oncotype DX and PAM50 support personalized care.
Samina Malik, Arif Malik, Shahzad Ahmad, Hassan Mohsin, Shazia Iqbal   +4 more
wiley   +1 more source

Identification of lncRNAs in peripheral blood mononuclear cells associated with sepsis immunosuppression based on weighted gene co-expression network analysis

Hereditas
Background Sepsis-induced immunosuppression involves complex molecular mechanisms, including dysregulated long noncoding RNAs (lncRNAs), which remain poorly understood. Objective We aimed to identify immunosuppression-related lncRNAs and their functional
Wenjia Zhang, Yan Li, Gang Li, Aijia Zhang, Wende Sun   +4 more
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Icariin inhibits proliferation and migration of VSMCs via LncRNA H19 competitively binding to HuR

Scientific Reports
Developing new anti-atherosclerotic agents and exploring their mechanistic actions is required. This study defined the molecular mechanism of icariin (ICA) in human aortic smooth muscle cells (HA-VSMCs) proliferation and migration by focusing on lncRNA ...
Yibing Zhang, Peng Huang, Min Li, Zhimin Fan   +3 more
doaj   +1 more source

RNA‐DNA Fusomer Fibers With Customizable Physicochemical, Mechanical, and Biological Properties for Next‐Generation Therapeutics

Small, EarlyView.
ABSTRACT We introduce RNA‐DNA fusomers, a new class of chemically synthesized oligonucleotides that combine the versatile properties of RNA and DNA within a single sequence and self‐assemble into higher‐order functional structures via a simple one‐pot annealing reaction.
Yasmine Radwan, Laura P. Rebolledo, Yelixza I. Avila, Elizabeth Skelly, Lauren Rackley, Julio Navas Hernandez, Renata de Freitas Saito, Laxmi K. Pandey, Hemani Chhabra, Alexander J. Lushnikov, Tatiane Katsue Furuya, Ana Luiza Lomba, Da Shi, Edward Cedrone, Ian Marriott, Morgan R. Chandler, Meni Wanunu, Aleksei Aksimentiev, Alexey V. Krasnoslobodtsev, Roger Chammas, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Bayesian Markov Random Rield Analysis for Protein Function Prediction Based on Network Data

, 2010
Inference of protein functions is one of the most important aims of modern biology. To fully exploit the large volumes of genomic data typically produced in modern-day genomic experiments, automated computational methods for protein function prediction ...
ter Braak, C.J.F., Yiannis A I Kourmpetis, Cajo J F ter Braak, Kourmpetis, Y.I.A., Roeland C H J van Ham, Ham, R.C.H.J., van, Aalt D J van Dijk, van Dijk, A.D.J., Bink, M.C.A.M., van Dijk Aalt D. J., Kourmpetis Yiannis A. I., van Ham Roeland C. H. J., Dijk, A.D.J., van, Bink Marco C. A. M., Braak, C.J.F., ter, Marco C A M Bink, van Ham, R.C.H.J., ter Braak Cajo J. F.   +17 more
core   +1 more source