Results 141 to 150 of about 699,235 (311)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Review of Load Frequency Control in Wind Energy Conversion System

open access: yesWind
The integration of renewable energy sources (RESs) into modern power systems has introduced significant challenges in maintaining system stability and reliability.
Welcome Khulekani Ntuli, Musasa Kabeya
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Sequential decentralized design of robust load frequency controllers in a multi-area power system [PDF]

open access: yes, 2002
The objective of the Load Frequency Control (LFC) is to maintain the frequency and to keep tie-line power flows within pre-specified values. In this paper a new systematic approach to design of sequential decentralized load frequency controllers for ...
Mitani, Yasunori   +2 more
core  

Innovative Load Frequency Control: Integrating Adaptive Backstepping and Disturbance Observers

open access: yesIEEE Access
Load frequency control (LFC) in large interconnected power systems is crucial for balancing electricity supply and demand while minimizing frequency deviations.
Javad Ansari   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

A direct A.C. to A.C. regenerative frequency and voltage converter [PDF]

open access: yes, 1980
Includes bibliographical references.The reliable variable speed operation of an a. c. machine over a wide speed range is a problem that has received attention for some time.
Case, Michael James
core  

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