Results 121 to 130 of about 12,777,871 (251)

A series-parallel load-resonant converter for a controlled-current arc-welding power supply [PDF]

A power supply incorporating a series-parallel load-resonant converter, capable of very efficient operation over a wide range of output power is presented. The series-parallel load-resonant converter is shown to have three pairs of resonant frequencies.
Pollock, Helen Geraldine Phyllis
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Takagi-Sugeno fuzzy gain controller for Vehicle-to-Grid (V2G) load frequency control

Systems and Soft Computing
Load Frequency Control (LFC) has gained more importance with the introduction of deregulated Renewable Energy Sources (RES) connectivity with the grid.
Marayati Marsadek, Farrukh Nagi, Navinesshani Permal, Agileswari AP Ramasamy, Aidil Azwin   +4 more
doaj   +1 more source

Application of Kharitonov's Theorem and its Results to Load Frequency Control

, 1998
The classical design of load-frequency controller is usually based on the conventionally tuned PI controllers. These controllers are designed for a particular operating point of the system.
Bevrani, Hassan
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Optimization of Frequency Stability in Hydraulic Load Frequency Control Systems Using Controllers with Filters

Andalas Journal of Electrical and Electronic Engineering Technology
This study meticulously investigates the design and analysis of a Load Frequency Control (LFC) system tailored explicitly for hydraulic power systems by employing diverse configurations of PID controllers, namely Proportional (P), Proportional-Integral ...
Heru Dibyo Laksono, Dhea Rahmadani Putri , Mumuh Muharam , Rizki Wahyu Pratama   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

The impact of increased renewable energy penetration and reduced inertia on the frequency nadir in a multi-area interconnected network based on the peninsula Malaysia national grid

Global Energy Interconnection
The increased adoption of renewable energy sources (RES) has left the power system grid with ever more decreasing inertia. The inertia plays a crucial part in mitigating frequency changes in the power system.
Ousama M.T. Ajami, Maadh S.J. Alkhusaibi, Rodney H.G. Tan, Farah Adilah Jamaludin, Mithulananthan Nadarajah   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Innovative Load Frequency Control: Integrating Adaptive Backstepping and Disturbance Observers

IEEE Access
Load frequency control (LFC) in large interconnected power systems is crucial for balancing electricity supply and demand while minimizing frequency deviations.
Javad Ansari, Mohamadreza Homayounzade, Ali Reza Abbasi   +2 more
doaj   +1 more source