Results 111 to 120 of about 12,777,871 (251)
Sequential decentralized design of load frequency controllers in multiarea power systems
A new systematic approach to design of sequential decentralized load frequency\ud controllers for multi-area power systems based on μ-synthesis is described.
Mitani, Yasunori +2 more
core
Amidst centralized and distributed frequency control in power systems
We propose a novel frequency control approach in between centralized and distributed architectures, that is a generalized continuous-time feedback control version of the dual decomposition optimization method.
GRAMMATICO, SERGIO +7 more
core +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Decentralised Load-frequency Control
We propose a numerical procedure to determine the load-frequency control of a power system composed of several interconnected areas. In order to decrease the associated implementation cost, the control law is constrained to have two different special ...
Geromel J.C., Peres P.L.D.
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
The modelling of electric power systems on the state space and an optimal control system known as Linear Quadratic Regulator (LQR) for designing the load frequency control system are realized in this paper. In order to obtain high quality electric energy
ADNAN KAKİLLİ +2 more
doaj +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Basado en un análisis estadístico de una base de datos en tiempo real se propone un procedimiento paradeterminar los diapasones de potencia activa necesarios para desarrollar un efectivo control de la frecuencia. A generalized approach
Antoino A Martínez García +3 more
doaj
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source

