Results 121 to 130 of about 1,494,355 (294)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

An SDN-enhanced load balancing technique in the cloud system.

, 2016
The vast majority of Web services and sites are hosted in various kinds of cloud services, and ordering some level of quality of service (QoS) in such systems requires effective load-balancing policies that choose among multiple clouds.
Choo, Hyunseung, Kang, Byungseok
core   +1 more source

Energy Aware Controller Load Balancing Based on Multi-Agent Deep Reinforcement Learning for Software-Defined Internet of Things

Journal of Computer Networks and Communications
Fluctuations in traffic within the Internet of Things (IoT) can affect the performance of the control plane. It is important to maintain stable control plane performance by load balancing strategies.
C. F. Lv, B. Li, J. Wei
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Load Balancing for Response Time

Journal of Algorithms, 1995
Summary: A centralized scheduler must assign tasks to servers, processing on-line a sequence of task arrivals and departures. Each task runs for an unknown length of time, but comes with a weight that measures resource utilization per unit time. The response time of a server is the sum of the weights of the tasks assigned to it. The goal is to minimize
openaire   +3 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

ELAB:end-host-based congestion aware load balancing for data center network

Tongxin xuebao, 2019
A good load balance mechanism is the key to effectively use the network of the data center network.In current production data center,ECMP is the de facto load balancing scheme.However,it has two drawbacks.1) the load balance unit is too coarse-grained,2)
Guo CHEN, Weifeng ZHANG
doaj   +2 more sources

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Caracterização computacional para alocação distribuída para uma configuração com interface natural de usuário [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Ciência da Computação, Florianópolis, 2015.Em um sistema distribuído heterogêneo, como grades computacionais, a escolha do sistema ...
Ferreira, Guilherme Maciel
core  

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source