Results 101 to 110 of about 83,057 (306)

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Impact of flange geometry on the ultimate axial load capacity of V-band clamps

, 2010
Modern turbochargers typically comprise a body in three parts; the turbine and compressor housings and the bearing housing. The preferred method of joining these three parts, in automotive applications, is to use a band clamp with a flat bottomed V ...
Barrans, Simon, Muller, Matthias, Barrans, S. M., Muller, M.   +3 more
core  

Experimental study on axial load-bearing capacity of grout-lifted compressible concrete-filled GFRP tube composite column

Meitan xuebao
To address the challenges of roadway along gob support under high-stress conditions, a grout-lifted compressible GFRP (Glass Fiber Reinforced Plastic) tube concrete composite support column structure was proposed.
Jun WANG, Zhaolong WU, Gang WANG, Shunzhang LYU   +3 more
doaj   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Heave induced reduction of friction capacity of pile embedded in clays

MATEC Web of Conferences, 2017
Installation of new piles may cause heave which influence friction capacity of existing piles. The heave can be observed from the difference in the elevation of existing pile heads recorded before and after the installation of new piles or through load ...
Setyo Budi Gogot, Wibowo Tantri Gondo
doaj   +1 more source

Effect of soil-pile contact parameters on pile bearing capacity value [PDF]

E3S Web of Conferences
The soil and foundation elements are fundamental to the behavior of a structure. When the foundation soil has a low capacity, it is necessary to transmit the loads to a deeper and more resistant layer, using deep foundations.
Campos Darym, Morandini Thiago, Ferreira Stéphanie, Camapum José, Cavalcante André, Ozelim Luan   +5 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Seismic capacity of building constructed in slip formed load bearing wall panels

, 2011
Constructing buildings using slip formed load bearing wall panels is becoming increasingly popular in Sri Lanka due to several advantages; low cost, environmental friendliness and rapid construction technique.
Moragaspitiya, Praveen, Susantha, K.A.S.
core  

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source