Results 81 to 90 of about 83,057 (306)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Experimental and Numerical Simulation Investigations on the Bearing Capacity of Stepped Variable-Section DX Piles under Vertical Loading

Buildings
As a new type of pile, the bearing characteristics of stepped variable-section DX piles (multi-joint extruded and expanded piles) are quite complicated; thus, their design concepts and pile-forming processes are still in the exploration stage, and their ...
Jinsheng Cheng, Lei Tong, Chuanzhi Sun, Hanbo Zhu, Jibing Deng   +4 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Static, dynamic and levitation characteristics of squeeze film air journal bearing: Designing, modelling, simulation and fluid solid interaction

, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Bearings today need to be able to run at very high speed, providing high positional accuracy for the structure that it supports, and requiring very little ...
Wang, Chao
core  

Load bearing capacity of fire rated light timber frame walls [PDF]

, 2021
Light timer frame (LTF) walls are made of solid timber elements (studs and tracks) and are usually protected by fire insulation materials (gypsum). This investigation finds the residual load bearing capacity of LTF walls after certain fire rating periods
Fonseca, E.M.M., Piloto, P.A.G.
core   +1 more source

Experimental and Numerical Investigation on the Ultimate Bearing Capacity of Axially Compressed Steel Tube Columns with Local Corrosion

Buildings
In this paper, 17 types of circular, hollow steel tube columns were designed for the axial compression test. A defect was corroded with an acid rain spray method.
Wei Fang, Tao Wang, Mengcheng Chen, Mingyang Zhang, Hong Huang, Kaicheng Xu, Qingqing Wen   +6 more
doaj   +1 more source

Instruments of Probabilistic Optimisation of Load Bearing Capacity and Reliability of Statically Indeterminate Complex Structures

Archives of Civil Engineering, 2014
The paper presents the method of probabilistic optimisation of load bearing capacity and reliability of statically indeterminate bar structures, and of coupling of members in kinematically admissible failure mechanisms (KAFM), which contain minimal ...
Kowal Z.
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source