Results 31 to 40 of about 354,609 (267)
Applied Sciences, 2021 This study aims to strengthen the flexural behavior of structural elements with external pre-stressing tendons, thereby improving their load-carrying capacity and increasing their resistance against the external load.
Gouda A. Mohamed +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The use of simplified methods for designing according to EC6 and safety of masonry structures
Budownictwo i Architektura, 2013 The article describes the calculation method of masonry walls loaded vertically according to PN-EN 1996-1-1 and PN-EN 1996-3. The Calculation method is given and the differences between Eurocode 6 and "old Polish standard" are indicated.
Wojciech Chruściel, Paweł Sulik
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Budownictwo i Architektura, 2013 In recent years, in our country are modernized and rebuilt several sections of railway lines, mainly main lines. The greater part is adapted to increased speeds.
Adam Wysokowski
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
LOAD-CARRYING CAPACITY OF SHEAR-LOADED BOLTED JOINTS [PDF]
, 2023 Bolted joints are the most common and primary form of joints in most machines. The directions of research in this area mostly relate to strength, stiffness, load-carrying capacity, causes of failure, temperature influences etc. Fitted and clamped group bolted joints shear-loaded with torque are analyzed in this paper.
Lazović, Tatjana +2 more
openaire
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Soil Compressibility under Irrigated Perennial and Annual Crops in a Semi-Arid Environment
Revista Brasileira de Ciência do SoloIn irrigated soils, a continuous state of high moisture reduces resistance of the soil to applied external forces, favouring compaction. The aim of this study was to evaluate the susceptibility to compaction of developed calcareous soils in irrigated ...
Rafaela Watanabe +4 more
doaj +1 more source