Results 51 to 60 of about 375,664 (266)
Compression behaviour of Q355 steel angles with local defect at bolt holes
Frontiers in MaterialsThis paper presents experimental and numerical studies on compression behaviour of equal-leg steel angles with bolted connection and subjected to local defect at the bolt hole.
Jinglu Zhang +5 more
doaj +1 more source
Load capacity ratios for structures [PDF]
Computer Methods in Applied Mechanics and Engineering, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Falach, Lior, Segev, Reuven
openaire +2 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
IEEE AccessAs robotics and materials science develop, origami mechanical structures have gradually attracted attention in the research field due to their lightweight, foldable, and multifunctional characteristics. As one of them, the water elastic origami mechanism,
Meng Xiao, Cuiying Yang, Shujie Gao
doaj +1 more source
Evaluation of a Current Vehicle Load Model Using Weigh-in-Motion Records: A Case in China
The Baltic Journal of Road and Bridge Engineering, 2016 In order to assess the vehicle load carrying capacity of existing bridges on the national highway G103 in Beijing, the vehicle load model for the practical traffic flow conditions needs to be determined.
Zigang Xu +4 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Friction, 2019 In this paper, a square textured parallel slider is considered for a study to improve the hydrodynamic performance of moving parts. The numerical method is employed for the analysis of a square texture with different bottom profiles: flat, triangle T1 ...
Nilesh D. Hingawe, Skylab P. Bhore
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source