Results 71 to 80 of about 1,598,056 (300)

TRANSFORMER LOAD CAPACITY AND ITS HEAT OUTPUT CAPACITY

open access: yes, 2022
The problem of transformer losses and their causes are studied and recommendations for their optimal values are given. Transformer heating and cooling methods are studied.
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Plugged hollow shaft makes fatigue-resistant shear pin [PDF]

open access: yes, 1966
Shear pin coupling with plugged hollow shaft provides required load capacity for shaft protection and has no groove to induce fatigue ...
Hankinson, T. W. E.
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Waterbomb Origami Mechanism Pneumatic Manipulator Design Based on DH Parameter Method and Symmetric Folding Hypothesis

open access: yesIEEE Access
As robotics and materials science develop, origami mechanical structures have gradually attracted attention in the research field due to their lightweight, foldable, and multifunctional characteristics. As one of them, the water elastic origami mechanism,
Meng Xiao, Cuiying Yang, Shujie Gao
doaj   +1 more source

Evaluation of a Current Vehicle Load Model Using Weigh-in-Motion Records: A Case in China

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2016
In order to assess the vehicle load carrying capacity of existing bridges on the national highway G103 in Beijing, the vehicle load model for the practical traffic flow conditions needs to be determined.
Zigang Xu   +4 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Multi-objective optimization of the design parameters of texture bottom profiles in a parallel slider

open access: yesFriction, 2019
In this paper, a square textured parallel slider is considered for a study to improve the hydrodynamic performance of moving parts. The numerical method is employed for the analysis of a square texture with different bottom profiles: flat, triangle T1 ...
Nilesh D. Hingawe, Skylab P. Bhore
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Hydrodynamic lubrication of rigid nonconformal contacts in combined rolling and normal motion [PDF]

open access: yes
A numerical solution to the problem of hydrodynamic lubrication of rigid point contacts with an isoviscous, incompressible lubricant was obtained. The hydrodynamic load-carrying capacity under unsteady (or dynamic) conditions arising from the combined ...
Brewe, D. E.   +2 more
core   +1 more source

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