Results 71 to 80 of about 376,913 (267)

Stress correction factor in load capacity estimation standard, JIS B 1759, for plastic gears

Journal of Advanced Mechanical Design, Systems, and Manufacturing
The present study is part of a series aimed at enhancing the reliability of JIS B 1759, ”Estimation of tooth bending strength of cylindrical plastic gears.” This study examined the stress correction factor converting the nominal tooth bending stress into
Ichiro MORIWAKI, Akio UEDA, Takao KOIDE, Morimasa NAKAMURA, Karsten STAHL, Thomas TOBIE   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Load capacity of hardened gear wheels machined with cubic boron nitride (CBN) wedges

Metalurgija, 2013
The paper presents the results of exploitation examination of gear wheels with hardened bearing surface. The gears under investigation have been finish machined by the method elaborated by the author, with a tool possessing wedges made of CBN (cubic ...
R. Talar, A. Stoić
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Cascading Failures in Power Grids: A Load Capacity Model with Node Centrality

Complex System Modeling and Simulation
Power grids, due to their lack of network redundancy and structural interdependence, are particularly vulnerable to cascading failures, a phenomenon where a few failed nodes—having their loads exceeding their capacities—can trigger a widespread collapse ...
Chaoyang Chen, Yao Hu, Xiangyi Meng, Jinzhu Yu   +3 more
doaj   +1 more source

Experimental verification of externally pressurized gas journal bearings with asymmetric gas supply (Supply gas pressure control operation using a small size test rig)

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2014
Externally pressurized gas journal bearings with an asymmetric gas supply mechanism have been developed by one of the authors. This bearing has a large load capacity compared with conventional symmetric gas supply bearings because low and high ...
Tomohiko ISE, Kazuya IMANISHI, Toshihiko ASAMI, Takahiro TOKUMIYA, Naoyuki TAKADA, Fumiyoshi KIMURA, Yoshiyuki YAMAGUCHI   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Experimental study on multi-decked protuberant foil thrust bearing with different number of thrust pads

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
Thrust bearing is an important component in high speed rotor bearing system. For the thrust bearing, the pad circumferential partition is recognized as an essential factor for the foil thrust bearing in hydrodynamic lubrication.
Tianwei LAI, Yu GUO, Wei WANG, Shuangtao CHEN, Yu HOU   +4 more
doaj   +1 more source