Results 61 to 70 of about 376,913 (267)

Design of flexural strengthening based on fib Bulletin 90 [PDF]

open access: yesArchives of Civil Engineering
This paper presents the analysis of intermediate and end debonding failure in slab strengthened using carbon tapes (Carbon Fiber Reinforced Polymer). The calculations are based on the more accurate method in the latest fib Bulletin 90.
Renata Kotynia, Monika Kaszubska
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Optimizing Load Capacity Predictions in Gas Foil Thrust Bearings: A Novel Full-Ramp Model

open access: yesLubricants
Gas film thickness significantly influences the performance prediction of Gas Foil Thrust Bearings (GFTB). However, the Classical Model (CM) for GFTBs exhibits inaccuracies in describing gas film thickness.
Ming Ying   +3 more
doaj   +1 more source

BEARING TYPE – CRITERIA, APPLICATIONS AND TECHNICAL RECOMMENDATIONS [PDF]

open access: yesRomanian Journal of Petroleum & Gas Technology
The choice of the suitable bearing type is a significant step in the mechanical design, which has a direct impact on the system performance, reliability, and efficiency.
Daniela Costache   +1 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Buckling Behaviour of Q355 Angles with Simulated Local Damages at Bolted Connections

open access: yesBuildings
Transmission towers in service are highly susceptible to corrosion caused by environmental conditions. It is crucial to assess the residual load capacity of corroded angles in transmission towers.
Cheng Xu, Hui-Qiang Yan, Shao-Bo Kang
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Experimentally Validated Nonlinear Analysis of Bridge Plate Girders with Deformations

open access: yesStudia Geotechnica et Mechanica, 2015
Comprehensive methodology of numerical nonlinear analysis of the consecutive phases in the structural behaviour of bridge plate girders with deformations is presented.
Kużawa Mieszko, Bień Jan
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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