Results 61 to 70 of about 132,191 (309)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Review of Connection Methods for Assembled Metro Prefabricated Components
Chengshi guidao jiaotong yanjiu［Objective］ The connection methods of prefabricated concrete components are crucial for the installation efficiency and structural stability of assembled metro systems.
DING Xianli, ZAN Zihui, WANG Ran
doaj +1 more source
Computer Science, 2021 The need for an internet network today is very important along with the development and progress of increasingly sophisticated data communications. With uses such as searching for information, the need to upload and download documents from the internet ...
Rizky Apriansyah Hadi +1 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Quality Analysis of Service Load Balancing Using PCC, ECMP, and NTH Methods
Jurnal Nasional Pendidikan Teknik Informatika (JANAPATI), 2023 One of the solutions to get a better quality of internet service is to utilize load balancing technology. We can use more than one different ISP (Internet Service Provider) which is then balanced with load balancing technology, where this technique is ...
Kurnianto Tri Nugroho +3 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Performance of reinforced concrete wall foundation connection under lateral cyclic load / Nurul ‘Aadila Saleh [PDF]
, 2012 High-rise buildings are typically designed wall and foundation to resist the load during windstorms and earthquakes. Although performance of reinforced concrete wall foundation connection under lateral cyclic load are generally understood for ...
Saleh, Nurul ‘Aadila
core
The Implementation of Load Balancing Using Per Connection Classifier Method Using Mikrotik RB1100 [PDF]
, 2023 The Implementation of Load Balancing Using Per Connection Classifier Method Using Mikrotik RB1100 By : Pedro Maldini Siagian 1) Hari Aspriyono 2) Eko Prasetiyo Rohmawan 2) Poltekkes Kemenkes Bengkulu as a university which has 2 ...
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source