Digital governance pressure and digital burnout among grassroots public sector employees: the mediating roles of cognitive load and negative affect. [PDF]
Wang Z, Wang T, Chen H.
europepmc +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
The Translational Biology of Temporomandibular Disorder Pain: Mechanisms, Biomarkers, and Therapeutic Perspectives. [PDF]
Firinciogullari EC, Alluri K, Yadav S.
europepmc +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
A multi-criteria economic and technical power optimization in intelligent off-electrical grid considering hybrid management of consumption and centralized participation of the hydrogen system. [PDF]
Sherov A +6 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Preparation and Performance Optimization of an Expansive Backfill Material for Active Roof Contact in End-Wall Mining. [PDF]
Lyu J, Song Z, Song B, Lin Y, Ma W.
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
A Sensor-Aware Physics-Based Framework for Continuous Smartphone Battery State and Lifetime Prediction. [PDF]
Wu Z, Dong W, Yang Z, Diao M.
europepmc +1 more source

