Results 101 to 110 of about 8,651,646 (342)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

MODIFICACIONES EN UN FLUJO DE CARGA POR LA INCLUSIÓN DE UN CONTROLADOR UNIFICADO DE FLUJOS DE POTENCIA MODIFICAÇÕES EM UM FLUXO DE CARGA PELA INCLUSÃO DE UM CONTROLADOR UNIFICADO DE FLUXOS DE POTÊNCIA MODIFICATIONS ON A POWER FLOW DUE TO INCLUSION OF A UNIFIED POWER FLOW CONTROLLER

open access: yesRevista EIA, 2009
El crecimiento de los sistemas de potencia y las condiciones de mercado dadas por los esquemas desregulados han evidenciado las limitantes técnicas y de operación que los sistemas eléctricos de potencia SEP tienen para abastecer la demanda bajo estrictas
JUAN PABLO RIVERA   +1 more
doaj  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Force-velocity correlations in a dense, collisional, granular flow [PDF]

open access: yes, 2005
We report measurements in a 2-dimensional, gravity-driven, collisional, granular flow of the normal force delivered to the wall and of particle velocity at several points in the flow. The wall force and the flow velocity are negatively correlated.
Dragulin, Sonia   +4 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

An analysis of experimental data on entrance effects in circular thrust bearings [PDF]

open access: yes
Empirical method for considering entrance effects in computing flow rates and load capacities of circular thrust ...
Carfagno, S. P.
core   +1 more source

Parallel Methods for Systems of Nonlinear Equations Applied to Load Flow Analysis [PDF]

open access: yes, 2013
A thesis submitted to the university of London in fulfillment of the requirements for the degree of Doctor of ...
Joubert, Adriaan
core  

Optimal Investment on Series FACTS Devices Considering Contingencies

open access: yes, 2016
Series FACTS devices are capable of relieving congestion and reducing generation costs in the power system. This paper proposes a planning model to optimally allocate TCSCs in the transmission network considering the base case and $N-1$ contingencies. We
Dimitrovski, Aleksandar   +2 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Sizing guidelines for grid-connected decentralised energy storage systems: single house application

open access: yesThe Journal of Engineering, 2019
Nowadays, the existing hierarchical, centrally controlled power grid faces new challenges due to the increase penetration of renewable sources, the need of implementing demand-side management and the 2020 and 2050 environmental targets.
Konstantina Panagiotou   +2 more
doaj   +1 more source

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