Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Application of the mobility power flow approach to structural response from distributed loading [PDF]
The problem of the vibration power flow through coupled substructures when one of the substructures is subjected to a distributed load is addressed. In all the work performed thus far, point force excitation was considered.
Cuschieri, J. M.
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Measurement and evaluation of swirl-type flow in labyrinth seals of conventional turbine stages [PDF]
, 1982 The effects of load factor and rotor eccentricity were determined on flow conditions in test series for two stages. The results indicate that swirl-type entry flow follows the rules of potential swirl.
Hauck, L.
core +1 more source
ExaGridPF: A Parallel Power Flow Solver for Transmission and Unbalanced Distribution Systems
, 2017 This paper investigates parallelization strategies for solving power flow problems in both transmission and unbalanced, three-phase distribution systems by developing a scalable power flow solver, ExaGridPF, which is compatible with existing high ...
Bachan, John, Chan, Cy, Wang, Bin
core +1 more source
, 2007 A key process within astronomy is the exchange of mass, momentum, and energy between diffuse plasmas in many types of astronomical sources (including planetary nebulae, wind-blown bubbles, supernova remnants, starburst superwinds, and the intracluster medium) and dense, embedded clouds or clumps.
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Sizing guidelines for grid-connected decentralised energy storage systems: single house application
The Journal of Engineering, 2019 Nowadays, the existing hierarchical, centrally controlled power grid faces new challenges due to the increase penetration of renewable sources, the need of implementing demand-side management and the 2020 and 2050 environmental targets.
Konstantina Panagiotou +2 more
doaj +1 more source
Parallel Methods for Systems of Nonlinear Equations Applied to Load Flow Analysis [PDF]
, 2013 A thesis submitted to the university of London in fulfillment of the requirements for the degree of Doctor of ...
Joubert, Adriaan
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source