Results 171 to 180 of about 430,420 (317)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Critical Loading Events for the Assessment of Medium-Span Bridges

, 2012
The Sixth International Conference on Computational Structures Technology Prague, Czech Republic 4-6 September 2002This paper describes the simulation of free-flowing traffic across bridges to predict the characteristic values for bridge load effects
O'Brien, Eugene J., Graves, S.A., Caprani, Colin C.   +2 more
core  

Influence of Curing-Induced Adhesive Behavior on Joint Formation and Mechanical Performance in CFRP/Al Hybrid Joints. [PDF]

Polymers (Basel)
Park CG, Park MW, Jin BJ, Shim JY.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Fast load flow algorithms

, 1977
New, fast and reliable algorithms for solving load-flow problems are presented in this thesis. Each of these algorithms iteratively solves a set of linear equations in terms of voltage magnitude squared and phase angles, and converges onto the final ...
Jalali-Kushki, Hossein
core  

Optimal DG allocation using the Dingo Optimization Algorithm: robust power loss reduction with concomitant voltage stability improvement in distribution and transmission networks. [PDF]

Sci Rep
Kotb H, Michael G, AboRas KM.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Development of a polychromatic flow cytometry panel for the evaluation of HIV-specific T cell responses

, 2009
Includes abstract.Includes bibliographical references (leaves 99-115).Investigating T cell responses in HIV infection has revealed several correlates of viral control, but their importance is not fully understood.
Naicker, Prinola
core  

Research on the Determination Method of Additional Safety Factor Margin for Ultradeep Well Pipe Strings under Multisource Loads. [PDF]

ACS Omega
Gao Y, Zhang H, Li X, Wu B, Chen Q, Cai B, Zhang H.   +6 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source